Full Schedule

6:00 AM - 6:30 PM PDT

Registration Open

Location: Summit Lobby

8:00 AM - 12:00 PM PDT

SPC01--Morning- Together We Thrive: A Team-based Approach to Address Medical Traumatic Stress in PwCF Across the Lifespan

Location: 335-336

Chair: – Cincinnati Children's Hospital Medical Center, Divisions of Behavioral Medicine and Clinical Psychology & Pulmonary Medicine

Chair: – Massachusetts General Hospital/Harvard Medical School

Speaker: – Joe DiMaggio Cystic Fibrosis Center

Speaker: – University of California San Francisco

Speaker: – University of Kentucky

Speaker: – University of Calgary

Speaker: – Jacobs School of Medicine and Biomedical Sciences, University at Buffalo

Speaker: – MaineHealth

Community Speaker: – Cystic Fibrosis Foundation

Community Speaker:

SW/PSYCH

8:00 AM - 5:00 PM PDT

SPC03--Role of Airway Clearance Techniques including Exercise as an ACT in an Era of Change

Location: 327-329

Chair: – Private Practice

Chair: – Royal Brompton Hospital, Guys and St Thomas's NHS Foundation Trust and NHLI, Imperial College, London

Speaker: – Provincial Health Services Authority

Speaker: – Wellstar MCG Health Children's Hospital of Georgia

Speaker: – Private Practice

PT&RT

8:00 AM - 5:00 PM PDT

SPC04--Nuts & Bolts for the New CF Team Member

Location: 343-344

Chair: – Dell Children's Medical Center of Central Texas

Chair: – Children's Hospital Los Angeles

Speaker: – Hospital of the University of Pennsylvania

Speaker: – Wellstar MCG Health Children's Hospital of Georgia

Speaker: – UNC Medical Center

Speaker: – Cystic Fibrosis Foundation

Speaker: – St. Luke's Cystic Fibrosis Center of Idaho

Speaker: – Cystic Fibrosis Foundation

Speaker: – UH Cleveland Medical Center / Rainbow Babies and Children's

Speaker: – Boston Children's Hospital

Community Speaker: – Cystic Fibrosis Foundation

Community Speaker: – UVA Data Core

Community Speaker: – Cystic Fibrosis Foundation/Primary Children's CF Center

Community Speaker: – Dylan Mortimer Art

Speaker: – Children's Hospital Colorado

Speaker: – Dell Children's Medical Center of Central Texas

Speaker: – Children's Hospital Los Angeles

NRS

9:00 AM - 1:00 PM PDT

PCM--Psychosocial Collaborative Meeting: Empathy in Action: Strengthening Our Collective Impact

Location: 323-325

Chair: – Cystic Fibrosis Center- AUMC, CHOG

Chair: – Boston Children's Hospital/Brigham and Women's Hospital

Speaker: – UVAHealth Adult Cystic Fibrosis Clinic

Speaker: – Boston Children's Hospital

Speaker: – Northwell Health

Speaker:

SW/PSYCH

1:00 PM - 5:00 PM PDT

SC01--CFRD 101 - Diagnosis, Diabetes Technology, & Dietary Management

Location: 331-332

Chair: – UH Rainbow Babies and Children's Hospital

Chair: – National Jewish Health/IMH

Speaker: – St. Michael's Hospital - Unity Health Toronto

Speaker: – Baylor College of Medicine

Speaker: – Naomi Berrie Diabetes Center/Columbia University Irving Medical Center

Speaker: – UH Rainbow Babies and Children's Hospital

Speaker: – National Jewish Health/IMH

CLIN

1:00 PM - 5:00 PM PDT

SC02--CF Nutrition 101 for Dietitians New to CF

Location: 345-346

Chair: – Children's Hospital of Philadelphia

Chair: – University of North Carolina Health

Speaker: – University of Louisville

Speaker: – New York Presbyterian/Columbia University Irving Medical Center

NTR

1:00 PM - 5:00 PM PDT

SC03--Bugs & Drugs: Addressing the Basics & Digging Deeper

Location: 347-348

Chair: – MUSC Health

Chair: – Dell Children’s Medical Center of Central Texas

Speaker: – Boston Children's Hospital

Speaker: – Wellstar MCG- Children's Hospital of Georgia

Speaker: – University of Texas Southwestern

Speaker: – UC San Diego Health

Speaker: – Children’s National Hospital

Speaker: – University of Utah Health

NRSPHARM

1:00 PM - 5:00 PM PDT

SPC02--Afternoon- Healing the Hurt: Managing Pain with Evidence-based Strategies

Location: 335-336

Chair: – Massachusetts General Hospital/Harvard Medical School

Chair: – Cincinnati Children's Hospital Medical Center, Divisions of Behavioral Medicine and Clinical Psychology & Pulmonary Medicine

Speaker: – UNC Chapel Hill

Speaker: – University of Alabama at Birmingham

Speaker: – University of Kansas Medical Center

Speaker: – Massachusetts General Hospital

Speaker: – University of Calgary

Speaker: – Jacobs School of Medicine and Biomedical Sciences, University at Buffalo

Community Speaker: – Cystic Fibrosis Foundation

SW/PSYCH

3:00 PM - 5:00 PM PDT

Family Forum Session

Location: 447-448

Chair: – Duke Hospital

Chair: – University of Michigan Health

3:00 PM - 5:00 PM PDT

DG01--Head, Shoulders, Knees, & Toes: Addressing Common Musculoskeletal Complaints in Patients with CF!

Location: 340-342

Chair: – Children's Minnesota

Chair: – Nebraska Medicine

Speaker: – University of Alabama at Birmingham

Speaker: – Nebraska Medicine

Speaker: – Children's Minnesota

Speaker: – Boston Children's Hospital

PT&RT

3:00 PM - 5:00 PM PDT

DG02--CF Pharmacy 101

Location: 333-334

Chair: – UofL Health Pulmonary Specialty Clinic

Chair: – Keck Medicine of USC Specialty Pharmacy

Speaker: – Nebraska Medicine

Speaker: – Children's Healthcare of Atlanta

Speaker: – UH Rainbow Babies & Children's Hospital

Speaker: – Riley Hospital for Children Indiana University Health

PHARM

3:00 PM - 5:00 PM PDT

DG03--Caring for All of Us- Health Equity Workforce Training

Location: Elliott Bay

Chair: – Seattle Children's Hospital

HEAC

3:00 PM - 5:00 PM PDT

Building Self-Trust: What It Is, Why It Matters & How to Support It in CF Care

Location: 323-325

Chair: – Cystic Fibrosis Foundation

Chair: – Qualitative and Health Experiences Research Lab, Dept. of Family Medicine and Community Health, University of Wisconsin-Madison Dept. of Family Medicine and Community Health

Chair: – See What I Mean LLC

Speaker: – Cystic Fibrosis Foundation

Speaker: – See What I Mean LLC

Speaker: – Qualitative and Health Experiences Research Lab, Dept. of Family Medicine and Community Health, University of Wisconsin-Madison Dept. of Family Medicine and Community Health

4:00 PM - 6:30 PM PDT

Poster Set-up Time

Location: Exhibit Hall

5:00 PM - 6:00 PM PDT

Welcome Happy Hour

Location: Level 5 Foyers

6:00 PM - 7:00 PM PDT

PHARM: Open Forum Discussion

Location: Elliott Bay

Chair: – Riley Hospital for Children at Indiana Unversity Health

PHARM

6:00 PM - 7:00 PM PDT

NRS: Open Forum Discussion

Location: 447-448

Chair: – Medical University of SC

Chair: – Phoenix Children's Hospital

Chair: – Cohen Children's Medical Center

NRS

6:00 PM - 7:00 PM PDT

NRS: APP Open Forum Discussion

Location: 347-348

Chair: – Stanford University

Chair: – Rush University Medical Center

Chair: – University of Minnesota - Pediatric CF Center

NRS

6:00 PM - 7:00 PM PDT

Open Forum Discussion: CF-WISE Activity

Location: 345-346

Chair: – University of Virginia

6:00 AM - 6:30 PM PDT

Registration Open

Location: Summit Lobby

6:30 AM - 8:00 AM PDT

Poster Set-up Time

Location: Poster Hall

7:45 AM - 9:45 AM PDT

PGR1D- Management of Anal Condylomas Before and After Lung Transplant in a Person with Cystic Fibrosis and HIV

Discussant:

7:45 AM - 9:45 AM PDT

PGR--Physicians Grand Rounds

Location: Ballroom 2

Chair: – UH Cleveland Medical Center / Rainbow Babies and Children's

Chair: – Helen DeVos Children's Hospital @ Corewell Health

CLIN

7:45 AM - 9:45 AM PDT

PGR1- Management of Anal Condylomas Before and After Lung Transplant in a Person with Cystic Fibrosis and HIV

Location: Ballroom 2

Speaker: – Inova Advanced Lung Disease and Transplant Department

7:45 AM - 9:45 AM PDT

PGR2- What Happens To The Aging CF Pancreas?

Location: Ballroom 2

Speaker: – Froedtert Hospital and the Medical College of Wisconsin

7:45 AM - 9:45 AM PDT

PGR3- When headaches are not due to sinusitis: B-Acute Lymphocytic Leukemia in our adolescent CF Patient.

Location: Ballroom 2

Speaker: – Boston Children Health Physicians

7:45 AM - 9:45 AM PDT

PGR4- When PERT is the Problem – A Challenging Case in CF Nutrition

Location: Ballroom 2

Speaker: – Doernbecher Children's/Oregon Health & Science University

7:45 AM - 9:45 AM PDT

W01--Pathogenesis of CF Airway Infection

Location: Ballroom 3

Chair: – National Jewish Health

Chair: – University of South Florida

IMI

7:45 AM - 9:45 AM PDT

W01.1- C-di-GMP-dependent and -independent envelope stress response systems converge in Pseudomonas aeruginosa surface sensing

Location: Ballroom 3

Speaker: – University of Washington

7:45 AM - 9:45 AM PDT

W01.2- CFTR mutation abrogates Prevotella mediated regulation of epithelial cell defense against Staphylococcus aureus

Location: Ballroom 3

Speaker: – University of Colorado School of Medicine

7:45 AM - 9:45 AM PDT

W01.3- Evolutionary diversification of Pseudomonas aeruginosa pre-infection impacts downstream host-pathogen interactions in a model of cystic fibrosis airway infection

Location: Ballroom 3

Speaker: – Carnegie Mellon University

7:45 AM - 9:45 AM PDT

W01.4- Investigating the effects of the cystic fibrosis infant gut microbiota on immune regulation

Location: Ballroom 3

Speaker: – Geisel School of Medicine at Dartmouth

7:45 AM - 9:45 AM PDT

W01.5- Stenotrophomonas maltophilia exhibits defensive multicellularity in response to a Pseudomonas aeruginosa quorum sensing molecule

Location: Ballroom 3

Speaker: – National Institutes of Health (NIH)

7:45 AM - 9:45 AM PDT

W02--Improving Access & Decreasing Costs of Care

Location: 423-425

Chair: – University of Rochester Medical Center

Chair: – UVAHealth Adult Cystic Fibrosis Clinic

HEAC

7:45 AM - 9:45 AM PDT

W02.1- Barriers that prevent healthcare professionals from asking about and addressing financial needs or social determinants of health

Location: 423-425

Speaker: – Dartmouth College

7:45 AM - 9:45 AM PDT

W02.2- Impact of integrated health system specialty pharmacy services on clinical and operational outcomes in patients with cystic fibrosis

Location: 423-425

Speaker: – Boston Children's Hospital

7:45 AM - 9:45 AM PDT

W02.3- Identifying cystic fibrosis programs with disproportionately disadvantaged patient populations: Methodology and implications for care

Location: 423-425

Speaker: – University of Alabama at Birmingham

7:45 AM - 9:45 AM PDT

W02.4- Exploring the Lived Experiences of Black and Hispanic/Latino People with CF: Insights from Qualitative Interviews

Location: 423-425

Speaker: – University of Washington

7:45 AM - 9:45 AM PDT

W02.5- Building a Pan-African collaborative network for cystic fibrosis: Early lessons and shared priorities

Location: 423-425

Speaker: – University of Nairobi

Speaker: – Brigham and Women’s Hospital, Division of Global Health Equity

7:45 AM - 9:45 AM PDT

W03--Cell-Specific Roles of CFTR in the Airways: Insights into Expression and Function

Location: 433-434

Chair: – University of North Carolina at Chapel Hill

Chair: – Cincinnati Children's Hospital Medical Center

APPTTPTAC/CFTR

7:45 AM - 9:45 AM PDT

W03.1- Generation of a robust cystic fibrosis transmembrane conductance regulator–specific immunolabeling protocol across cell cultures and tissues.

Location: 433-434

Speaker: – Cystic Fibrosis Foundation Therapeutics Lab

7:45 AM - 9:45 AM PDT

W03.2- Which cells to target in the airway epithelium – finding an answer with temporospatial control of adenine base editing

Location: 433-434

Speaker: – Faculty of Sciences, University of Lisboa

7:45 AM - 9:45 AM PDT

W03.3- CFTR function in alveolar type 1 cells is critical to alveolar defense against S. aureus

Location: 433-434

Speaker: – Icahn School of Medicine at Mount Sinai

7:45 AM - 9:45 AM PDT

W03.4- Bicarbonate-secreting pulmonary ionocytes clusters modulate mucus viscosity in swine distal airway

Location: 433-434

Speaker: – University of Saskatchewan, College of Medicine, Department of Anatomy Physiology and Pharmacology

7:45 AM - 9:45 AM PDT

W03.5- Ferret Airway Glandular Myoepithelial Cells Exhibit Regenerative Potential with Enhanced CFTR Function of Progeny Epithelia

Location: 433-434

Speaker: – Medicine-Pulmonary/Allergy/Critical Care

7:45 AM - 9:45 AM PDT

DG04--Trivia Night

Location: 343-344

Chair: – University Of Rochester Medical Center

Chair: – The Children's Hospital of Philadelphia

Speaker: – University Of Rochester Medical Center

Speaker: – The Children's Hospital of Philadelphia

PT&RT

7:45 AM - 9:45 AM PDT

DG05--Education Update

Location: 345-346

Chair: – Levine Children's

Chair: – University of Pittsburgh

Speaker: – Rady Children's Hosptial- San Diego

Speaker: – Primary Children's Cystic Fibrosis Center

Speaker: – TTUHSC Department of Pediatric Pulmonology CF Center

Community Speaker:

Community Speaker: – CF parent

NRS

7:45 AM - 9:45 AM PDT

DG06--Chameleon Color Change: Adapting to the Changing CF Pharmacy Landscape

Location: 331-332

Chair: – WellstarMCG/Children's Hospital of Georgia

Chair: – Baylor College of Medicine- Pediatrics/Texas Children's Hospital

Speaker: – University of North Carolina Health

Speaker: – UNC Healthcare

Speaker: – Children's of Alabama

Community Speaker: – Mosaic Life Care

PHARM

7:45 AM - 9:45 AM PDT

DG07--Nuts & Bolts for CF Genetic Counselors

Location: 335-336

Chair: – Columbia University Irving Medical Center

Chair: – Children's Minnesota - Medical Genetics

Speaker: – University of Pennsylvania

Speaker: – University of Rochester Medical Center, Clinical Genetics

Speaker: – St. Vincent Hospital - Medical Genetics

CLIN

7:45 AM - 9:45 AM PDT

DG08--Strengthening Resilience Through Patient Peer Support Programs

Location: 347-348

Chair: – Medical University of South Carolina

Chair: – Adult Cystic Fibrosis Center of Central Texas

Speaker: – Phoenix Children's Hospital

Speaker: – Dell Children's Medical Center of Central Texas/The Center for Resiliency

Speaker: – University of Washington

Community Speaker: – Cystic Fibrosis Research Institute

NRS

7:45 AM - 9:45 AM PDT

DG09--Metabolic Health & Cardiovascular Disease Risk

Location: 320-322

Chair: – Billings Clinic

Chair: – Cystic Fibrosis Center of Southern Nevada

Speaker: – University of Minnesota

Speaker: – University of California Los Angeles

Speaker: – Washington University School of Medicine in St. Louis

Speaker: – Emory University School of Medicine

Speaker: – University of Virginia

NTR

7:45 AM - 9:45 AM PDT

DG10--Upholding Integrity: Ethics in Practice

Location: 333-334

Chair: – Northwestern University

Chair: – University of Alabama at Birmingham

Community Speaker: – The University of Alabama at Birmingham

Speaker: – Tulane Medical/ Manning Family Children's

Speaker: – University of Alabama at Birmingham

Speaker: – UTSW

Speaker: – NYU Langone Pulmonary & Critical Care

Speaker: – West Virginia University

SW/PSYCH

7:45 AM - 9:45 AM PDT

DG11--Research Coordinator Updates & Special Topics

Location: 327-329

Chair: – UPMC Children's Hospital of Pittsburgh

Chair: – University of Alabama at Birmingham

Speaker: – University of Alabama at Birmingham

Speaker: – TDN Coordinating Center, Seattle Children's Research Institute

Speaker: – University of Pittsburgh

Speaker: – University of Wisconsin-Madison

Speaker: – Cystic Fibrosis Foundation

Speaker: – Adult CF Center, National Jewish Health

CLIN

7:45 AM - 9:45 AM PDT

DG12--Adjusting & Thriving After a CFRD Diagnosis

Location: 340-342

Chair: – Stanford School of Medicine

Chair:

Speaker: – Stanford School of Medicine

Speaker: – Massachusetts General Hospita

Community Speaker:

Speaker: – Oregon Health & Science Unversity

SW/PSYCH

9:00 AM - 9:50 AM PDT

RFPT01--Therapeutic Targeting of Inflammation in CF

Location: Theater B Exhibit Hall

Chair: – Massachusetts General Hospital

Chair: – Emory University/Childrens Atlanta

APPTT

9:00 AM - 11:00 AM PDT

Coffee Break

9:00 AM - 5:00 PM PDT

Exhibit & Poster Hall Open

10:15 AM - 11:45 AM PDT

TPS01--Pharmacotherapy

Location: Theater A Exhibit Hall

Chair: – St. Luke's Cystic Fibrosis Center of Idaho

Chair: – Stanford Medicine Children's Health

PHARM

10:15 AM - 11:45 AM PDT

Tobramycin pharmacokinetics in pediatric people with cystic fibrosis on maintenance azithromycin

Location: Theater A Exhibit Hall

Speaker: – Riley Hospital for Children at Indiana Unversity Health

10:15 AM - 11:45 AM PDT

Insurance approval rates and barrier to access for vanzacaftor-tezacaftor-deutivacaftor at a single pediatric CF center

Location: Theater A Exhibit Hall

Speaker: – Child

10:15 AM - 11:45 AM PDT

The shenanigans continue: alternative funding program evolutions and CF care

Location: Theater A Exhibit Hall

Speaker: – Cystic Fibrosis Foundation

10:15 AM - 11:45 AM PDT

Implementation of Elexacaftor/Tezacaftor/Ivacaftor (ETI) Side Effect (SE) Review and Documentation for Pediatric Cystic Fibrosis (CF) Population

Location: Theater A Exhibit Hall

Speaker: – Ascension Seton SCC; Dell Children's Medical Center

10:15 AM - 11:45 AM PDT

Elexacaftor/tezacaftor/ivacaftor concentrations in pediatric cystic fibrosis patients on modified dosing regimens

Location: Theater A Exhibit Hall

Speaker: – UNC Medical Center

10:15 AM - 11:45 AM PDT

Dose optimization of omadacycline for the treatment of NTM pulmonary disease using a PBPK modeling approach

Location: Theater A Exhibit Hall

Speaker: – University of Southern California

10:15 AM - 11:45 AM PDT

Bridging Gaps in Access: Prior Authorization Challenges in CFTR Modulator Therapies. A Quality improvement Project

Location: Theater A Exhibit Hall

Speaker: – WVU Medicine

10:15 AM - 11:45 AM PDT

Pregnancy-related effect on elexacaftor, tezacaftor and ivacaftor pharmacokinetics in cystic fibrosis women

Location: Theater A Exhibit Hall

Speaker: – aU1343, Pharmacologie et évaluations thérapeutiques chez l'enfant et la femme enceinte, Inserm, Université Paris Cité, Paris (France)

10:15 AM - 11:45 AM PDT

The waiting game: Exploring deferred CFTR modulator initiation in pediatric cystic fibrosis care

Location: Theater A Exhibit Hall

Speaker: – University of Michigan

10:15 AM - 11:45 AM PDT

Increasing CF Ambulatory Pharmacist Support using a Shared Specialty Position 

Location: Theater A Exhibit Hall

Speaker: – Children's Wisconsin

10:15 AM - 12:15 PM PDT

W04--How to Survive & Thrive in a Small CF Center

Location: 427-429

Chair: – McLane Children's Hospital

Chair: – Medical University of South Carolina

NRS

10:15 AM - 12:15 PM PDT

W04.1- Addition of outpatient clinical pharmacy services can reduce nursing time spent on CF medication access challenges

Location: 427-429

Speaker: – UW Health Kids

10:15 AM - 12:15 PM PDT

W04.2- Train-the-Trainer Success in Low-Resource Areas: Quality Improvement Training for Establishing a CF Center in Formosa, Argentina.

Location: 427-429

Speaker: – Hospital Lagomaggiore

10:15 AM - 12:15 PM PDT

W04.3- Empowering the cystic fibrosis team: Initiating and accelerating quality improvement in a pediatric center

Location: 427-429

Speaker: – University of Missouri

10:15 AM - 12:15 PM PDT

W04.4- LEAP Principals

Location: 427-429

Speaker: – University of Minnesota

10:15 AM - 12:15 PM PDT

W04.5- Small Center Successes

Location: 427-429

Speaker:

Speaker: – Parkview Regional Medical Center

10:15 AM - 12:15 PM PDT

W05--Year in Review

Location: 431-432

Chair: – IU Health

Chair: – The Johns Hopkins Hospital

PT&RT

10:15 AM - 12:15 PM PDT

W05.1- Exercise capacity as a functional health marker in adolescents and young adults with cystic fibrosis: Impact of physical activity and sports participation

Location: 431-432

Speaker: – Johns Hopkins Hospital

10:15 AM - 12:15 PM PDT

W05.2- Active vs Passive Airway Clearance Technique

Location: 431-432

Speaker: – Adult CF Center of Central Texas

10:15 AM - 12:15 PM PDT

W05.3- Changes in Airway Clearance and Nebulized Therapies in Children on ETI

Location: 431-432

Speaker: – Cincinnati Children's Hospital

10:15 AM - 12:15 PM PDT

W05.4- Adherence and perspectives of CF patients and caregivers on airway clearance therapies before and after elexacaftor/tezacaftor/ivacaftor

Location: 431-432

Speaker:

10:15 AM - 12:15 PM PDT

W05.5- Feasibility of implementing the Alfred Step Test Exercise Protocol (A-STEP) in a pediatric CF clinic

Location: 431-432

Speaker: – Johns Hopkins Hospital

10:15 AM - 12:15 PM PDT

W06--Food for Thought: Best of Nutrition Research

Location: Signature Room

Chair: – University Hospitals

Chair: – Children's Hospital of Philadelphia

NTR

10:15 AM - 12:15 PM PDT

W06.1- Impact of Elexacaftor/Tezacaftor/Ivacaftor therapy on gastrointestinal inflammation, motility, and symptoms in Cystic Fibrosis: A multicenter prospective study

Location: Signature Room

Speaker: – Hadassah Medical Center and the Faculty of Medicine

10:15 AM - 12:15 PM PDT

W06.2- Correlations between skeletal muscle mass, BMI z-score, and exercise capacity in pediatric CF using bioelectrical impedance analysis

Location: Signature Room

Speaker: – Johns Hopkins Hospital

10:15 AM - 12:15 PM PDT

W06.3- A multi-center study of non-invasive colorectal cancer evaluation in Cystic Fibrosis (NICE-CF)

Location: Signature Room

Speaker: – Saint Louis University

10:15 AM - 12:15 PM PDT

W06.4- Baseline body composition and sarcopenia measures of adults with preserved lung function in the STRONG-CF Study

Location: Signature Room

Speaker: – Massachusetts General Hospita

10:15 AM - 12:15 PM PDT

W06.5- Modifiable Predictors of Beta-Cell Function in Adults with Cystic Fibrosis: The Role of Body Composition and Sugar Intake

Location: Signature Room

Speaker: – Emory University

10:15 AM - 12:15 PM PDT

W07--Agnostic Avenues: Alternatives to CF Gene Therapy

Location: 435

Chair: – The Ohio State University

Chair: – University of Illinois at Urbana-Champaign

APPTTPTAC/CFTR

10:15 AM - 12:15 PM PDT

W07.1- Elucidating the mechanism of ENaC activity reduction by CC-90009

Location: 435

Speaker: – UNC-Chapel Hill

10:15 AM - 12:15 PM PDT

W07.2- Novel readthrough compounds for the treatment of cystic fibrosis patients with nonsense mutations

Location: 435

Speaker: – INSERM

10:15 AM - 12:15 PM PDT

W07.3- Pulmonary delivery of circular RNA for cystic fibrosis therapy

Location: 435

Speaker: – University of Michigan

10:15 AM - 12:15 PM PDT

W07.4- Molecular prosthetics restore anion movement in cystic fibrosis intestinal models

Location: 435

Speaker: – University of Illinoit at Urbana-Champaign

10:15 AM - 12:15 PM PDT

W07.5- Restoration of anion transport to W1282X-CFTR expressing human bronchial epithelial cells by synthetic anion transporters

Location: 435

Speaker: – University of Bristol and Macquarie University

10:15 AM - 12:15 PM PDT

W08--Best Practices & Approach to Clinical Research, Including Community Engagement

Location: Ballroom 1

Chair: – National Jewish Health

Chair: – Boston Children's Hospital

CLIN

10:15 AM - 12:15 PM PDT

W08.1- Empowering Voices: The Personal Impact and Value of Community Participation in CF Research

Location: Ballroom 1

Speaker: – Cystic Fibrosis Foundation

10:15 AM - 12:15 PM PDT

W08.2- Paving the way: Integrating research education into clinic to forge new partnerships

Location: Ballroom 1

Speaker: – University of Vermont Medical Center

10:15 AM - 12:15 PM PDT

W08.3- Decreasing Cystic Fibrosis (CF) Foundation Patient Registry (CFFPR) encounter data entry time

Location: Ballroom 1

Speaker: – The University of Texas at Austin/Ascension

10:15 AM - 12:15 PM PDT

W08.4- The Research Coordinator Recruitment Experience in LTx READY CF 2, a multicenter trial of lung transplant education

Location: Ballroom 1

Speaker: – University of Washington

10:15 AM - 12:15 PM PDT

W08.5- Development of a consent communication framework to support values-aligned enrollment decision-making in cystic fibrosis clinical research

Location: Ballroom 1

Speaker: – Seattle Children's Hospital

10:15 AM - 12:15 PM PDT

W09--Gastrointestinal Involvement in CF

Location: Terrace Suite

Chair: – Nationwide Children's Hospital/The Ohio State University

Chair: – University of Pittsburgh

EPP

10:15 AM - 12:15 PM PDT

W09.1- CFTR Modulators Suppress CF Pancreas and Pancreatic Duct Cancer Cell Proliferation by Targeting Cell Cycle Pathway Genes

Location: Terrace Suite

Speaker: – Pediatrics

10:15 AM - 12:15 PM PDT

W09.2- Metabolic shifts in the Cystic Fibrosis mouse small intestine: Potential transcriptional drivers of glycolysis

Location: Terrace Suite

Speaker: – Case Western Reserve University

10:15 AM - 12:15 PM PDT

W09.3- Changes in fecal microbiome and relationships with gut inflammation and abdominal symptoms over 6 months of treatment with Elexacaftor/Tezacaftor/Ivacaftor in people with CF – results from RECOVER

Location: Terrace Suite

Speaker: – RCSI University of Medicine and Health Sciences

10:15 AM - 12:15 PM PDT

W09.4- A “gut-on-a-chip” model to study the gut-EN-sensory neuron interface in CF

Location: Terrace Suite

Speaker: – University of Saskatchewan

10:15 AM - 12:15 PM PDT

W09.5- Differences in Gastric Slow Wave Propagation in Youth and Young Adults with CF Compared to Healthy Controls

Location: Terrace Suite

Speaker: – Nationwide Children's Hospital

10:15 AM - 12:15 PM PDT

W10--Airway Differentiation, Pathogenesis, & Repair

Location: 436

Chair: – Boston University/Boston Medical Center

Chair: – University of Michigan Medical School

APPTT

10:15 AM - 12:15 PM PDT

W10.1- Pulmonary ionocyte specific CFTR reactivation restores chloride absorption and secretion in cystic fibrosis

Location: 436

Speaker:

10:15 AM - 12:15 PM PDT

W10.2- Investigating the differentiation and function of pulmonary ionocytes from human induced pluripotent stem cells.

Location: 436

Speaker: – Boston Children's Hospital

10:15 AM - 12:15 PM PDT

W10.3- .IL-1beta drives mucociliary airway epithelial remodeling by disrupting multiciliated cell fate and ciliogenesis programs

Location: 436

Speaker: – University of Colorado Anschutz Medical Campus

10:15 AM - 12:15 PM PDT

W10.4- Molecular pathways mediating loss of unique distal airway secretory cells in CF

Location: 436

Speaker:

10:15 AM - 12:15 PM PDT

W10.5- Modulating LEF1 to Improve Gene Editing Efficiency in Human Bronchial Stem Cells from people with Cystic Fibrosis.

Location: 436

Speaker: – Nationwide Children's Hospital

10:15 AM - 12:15 PM PDT

W11--Topical Advancements in CFTR Biology

Location: 420-422

Chair: – Faculty of Sciences, University of Lisboa

Chair: – Emory University School of Medicine

PTAC/CFTR

10:15 AM - 12:15 PM PDT

W11.1- Nonviral delivery of chemically modified suppressor tRNA for overcoming nonsense mutations in cystic fibrosis

Location: 420-422

Speaker: – University of Toronto

10:15 AM - 12:15 PM PDT

W11.2- Nascent chain misfolding slows translation and stimulates co-translational mRNA decay

Location: 420-422

Speaker: – Johns Hopkins University School of Medicine

10:15 AM - 12:15 PM PDT

W11.3- Role of cholesterol on CFTR single channel characteristics and potential cholesterol binding domains

Location: 420-422

Speaker: – Emory University

10:15 AM - 12:15 PM PDT

W11.4- Are there liabilities of codon optimization: Assessment of codon optimization methods in primary Human Bronchial Epithelial (hBE) cells.

Location: 420-422

Speaker: – CFFT Lab, Cystic Fibrosis Foundation, Lexington, MA, USA

10:15 AM - 12:15 PM PDT

W11.5- Airway targets for CF gene therapies: Development of a tool for the in vitro assessment of anion transport in common and rare cell types of human airway epithelium

Location: 420-422

Speaker: – City St George's, University of London

10:15 AM - 12:15 PM PDT

W12--Psychosocial Research Showcase

Location: Flex A

Chair: – Michigan Medicine Department of Pediatrics, CS Mott Children's Hospital

Chair: – Boston Children's Hospital

SW/PSYCH

10:15 AM - 12:15 PM PDT

W12.1- Navigating school with cystic fibrosis: Perspectives of people with CF and their caregivers

Location: Flex A

Speaker: – Cincinnati Children's Hospital

10:15 AM - 12:15 PM PDT

W12.2- Caregiver perspectives on illness burden and social support needs in the context of cystic fibrosis management: A mixed-methods study

Location: Flex A

Speaker: – Children’s National Hospital

10:15 AM - 12:15 PM PDT

W12.3- Impact of a smoking cessation intervention on hair nicotine levels in children with CF: Results from Clinical Effort Against Smoke Exposure in CF (CEASE-CF)

Location: Flex A

Speaker: – University of Alabama at Birmingham

10:15 AM - 12:15 PM PDT

W12.4- Associations among body image dissatisfaction, body esteem, mental health, and elexacaftor/tezacaftor/ ivacaftor (ETI) adherence in people with cystic fibrosis.

Location: Flex A

Speaker: – University of Colorado School of Medicine/Children's Hospital Colorado

10:15 AM - 12:15 PM PDT

W12.5- Adverse association between gastrointestinal disorders and anxiety/depression among people with cystic fibrosis

Location: Flex A

Speaker: – Cleveland Clinic Children's Hospital

10:15 AM - 12:15 PM PDT

W13--Epidemiology in Action: Insights from CF Registries & Beyond

Location: Ballroom 2

Chair: – Cystic Fibrosis Canada

Chair: – Cystic Fibrosis Foundation

CLIN

10:15 AM - 12:15 PM PDT

W13.1- Clinical characteristics and outcomes of people with cystic fibrosis with homozygous minimal function genotypes: Comparison to those with F508del/minimal function genotypes

Location: Ballroom 2

Speaker: – Case Western Reserve University

10:15 AM - 12:15 PM PDT

W13.2- Hospitalizations during the first two years of life in infants and young children with cystic fibrosis.

Location: Ballroom 2

Speaker: – Columbia University Irving Medical Center

10:15 AM - 12:15 PM PDT

W13.3- The changing nature of Canadian CF mortality in the post-modulator era.

Location: Ballroom 2

Speaker: – Cystic Fibrosis Canada

10:15 AM - 12:15 PM PDT

W13.4- Long term causal effects of ivacaftor on airway microbiology and lung function outcomes in people with cystic fibrosis: An emulation of target trials with the U.S. CF Foundation Patient Registry data

Location: Ballroom 2

Speaker:

10:15 AM - 12:15 PM PDT

W13.5- Medication adherence to cystic fibrosis transmembrane conductance regulator (CFTR) modulators: Analysis on the French cystic fibrosis population from 2012-2020

Location: Ballroom 2

Speaker: – Research on Healthcare Performance (RESHAPE), INSERM U1290, Université Claude Bernard Lyon 1

10:15 AM - 12:15 PM PDT

W14--Management of Infections & Inflammation in CF

Location: 423-425

Chair: – Emory University

Chair: – University of Cincinnati

IMI

10:15 AM - 12:15 PM PDT

W14.1- Leveraging bacterial iron uptake to potentiate antibiotic efficacy

Location: 423-425

Speaker: – Cedars-Sinai Medical Center

10:15 AM - 12:15 PM PDT

W14.2- Co-morbidities alter immune response and drive increased Pseudomonas abundance during viral infection in the airways of people with cystic fibrosis

Location: 423-425

Speaker: – Geisel School of Medicine at Dartmouth

10:15 AM - 12:15 PM PDT

W14.3- Using experimental evolution to weaponize bacteriophages for chronic Burkholderia cenocepacia infections in patients with cystic fibrosis

Location: 423-425

Speaker: – University of Pittsburgh

10:15 AM - 12:15 PM PDT

W14.4- Increased concentrations of mucin impede Staphylococcus aureus growth in synthetic cystic fibrosis sputum medium

Location: 423-425

Speaker: – University of Alabama at Birmingham

10:15 AM - 12:15 PM PDT

W14.5- AVP10 is a novel anti-viral peptide with reduced activity in the CF airway.

Location: 423-425

Speaker: – Kansas University Medical Center

10:15 AM - 12:15 PM PDT

W15--New Horizons in CF Newborn Screening: Advancements & Updates

Location: Ballroom 3

Chair: – Center for Public Health Innov

Chair: – Department of Pediatrics, Division of Pulmonology, Asthma, Cystic Fibrosis, and Sleep, Emory University School of Medicine

CLIN

10:15 AM - 12:15 PM PDT

W15.1- Reducing the age at first event in infants with a positive cystic fibrosis newborn screen in Arkansas: A quality improvement initiative

Location: Ballroom 3

Speaker: – University of Arkansas for Medical Sciences

10:15 AM - 12:15 PM PDT

W15.2- CF Newborn Screening Notification Practices and Time to Evaluation

Location: Ballroom 3

Speaker: – Children's Hospital of Philadelphia

10:15 AM - 12:15 PM PDT

W15.3 - Ohio CF Newborn Screening Collaborative – Moving Ohio forward

Location: Ballroom 3

Speaker: – Nationwide Children's Hospital

10:15 AM - 12:15 PM PDT

W15.4- Longitudinal Evaluation of a High Functioning CF Newborn Screening Program.

Location: Ballroom 3

Speaker: – Connecticut Childrens Medical Center

10:15 AM - 12:15 PM PDT

W15.5- Cystic fibrosis newborn screening: Policy and finance considerations for adopting Next-Generation Sequencing and reducing disparities

Location: Ballroom 3

Speaker: – Center for Public Health Innov

12:15 PM - 2:30 PM PDT

Visit Exhibits and Posters (Refreshments Available)

12:30 PM - 1:20 PM PDT

FSC01-- A Conversation with Scott Bell

Location: Fireside Chat A Exhibit Hall

Speaker: – Gold Coast University Hospital

Facilitator: – University of Toronto

CLIN

12:30 PM - 1:20 PM PDT

FSC02--A Conversation with James Chmiel

Location: Fireside Chat B Exhibit Hall

Speaker: – Indiana University School of Medicine

Facilitator: – Washington University in St. Louis

APPTT

12:30 PM - 1:20 PM PDT

RFPT02--Advanced QI Methods at Work

Location: Theater C Exhibit Hall

Chair: – Children's Health/UTSW

Chair: – OHSU

CLIN

12:30 PM - 1:20 PM PDT

RFPT03--Feeding the Future

Location: Theater B Exhibit Hall

Chair: – Loyola University Health System

Chair: – Hasbro Children's Hospital

NTR

12:30 PM - 2:00 PM PDT

Junior Investigators: Top 10 Poster Judging Time

Chair: – Massachusetts General Hospital/Harvard Medical School

Chair: – Indiana University

Chair: – Columbia University Irving Medical Center

Chair: – Emory University School of Medicine

Judge: – University of Pennsylvania

Judge: – Joe DiMaggio Cystic Fibrosis Center

Judge: – Department of Pediatrics, Medical College of Wisconsin, Children's Wisconsin

Judge:

Judge: – Cystic Fibrosis Foundation

Judge:

Judge: – University of Washington and VA Puget Sound Health Care System

Judge: – University of Michigan

Judge: – University of North Carolina

Judge: – University of Washington

Judge: – Yale University

12:30 PM - 2:00 PM PDT

LL01--So Many Guidelines, So Little Time

Location: 347-348

Chair: – Northwell Health

Chair: – Emory University School of Medicine

Speaker: – Stanford Medicine Children's Health

Speaker: – Northwell Lenox Hill Hospital

Speaker: – Emory University School of Medicine

Community Speaker:

SW/PSYCH

12:30 PM - 2:00 PM PDT

LL02--Equity in Every Line: Using Words Wisely to Expand Equity & Representation in Writing

Location: 323-325

Chair: – University of Kansas Health System

Chair: – University of Vermont Medical Center

Speaker: – University of Kansas Health System

Speaker: – University of Vermont Medical Center

HEACSW/PSYCH

12:30 PM - 2:00 PM PDT

LL03--From Symptoms to Solutions: Diagnosing & Collaboration for the Gut-Brain Axis in Bloating

Location: 333-334

Chair: – Oregon Health and Science University

Chair: – Massachusetts General Hospital

Speaker: – Doernbecher Children's Hospital, Oregon Health & Science University

Speaker: – Rutgers Robert Wood Johnson Medical School

Speaker: – Saint Louis University

Speaker: – Massachusetts General Hospital

NTR

12:30 PM - 2:00 PM PDT

LL04--Finding Your Calm: Strategies for Managing Pulmonary Function Testing Anxiety

Location: 320-322

Chair: – UH Rainbow Babies and Children's Hospital

Speaker: – University of Kentucky

Speaker: – University Hospitals Cleveland Medical Center

Speaker: – Banner University Medicine - Tucson

Community Speaker: – Breathe Bravely

PT&RT

12:30 PM - 2:00 PM PDT

LL05--Which Cell Types Are the Ideal Therapeutic Targets?

Location: 331-332

Chair: – Harvard Medical School

Chair: – Marsico Lung Institute/Cystic Fibrosis Research Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA

Speaker: – University of Alabama at Birmingham

Speaker: – University of Iowa

Speaker: – University of Saskatchewan

PTAC/CFTR

12:30 PM - 2:00 PM PDT

LL06--The Role of The Family In Research & Care

Location: 335-336

Chair: – Children's Hospital of Orange County

Chair: – New York Medical College / Boston Children's Health Physicians

Speaker: – Baylor College of Medicine, Texas Children's Hospital

Speaker: – Fiancée of CF Patient

Speaker: – Cohen Children's Medical Center, Northwell Health System

Speaker: – Cohen Children's/Northwell Health

Speaker: – National Jewish Health

CLIN

12:30 PM - 2:00 PM PDT

Roundtables: Group 1

Location: 345 - 346

12:30 PM - 2:00 PM PDT

RT01.1- Beyond Access Issues - Expanding Roles for Pharmacy Technicians in CF Care

Location: 345 - 346

Facilitator: – Primary Children's Hospital

PHARM

12:30 PM - 2:00 PM PDT

RT01.2- Saving the Best Last - Palliative Care Innovations

Location: 345 - 346

Facilitator: – Geisinger

PHARM

12:30 PM - 2:00 PM PDT

RT01.3- Cheat Codes Please: Finding Success with Copay Assistance Programs

Location: 345 - 346

Facilitator: – Johns Hopkins Hospital

PHARM

12:30 PM - 2:00 PM PDT

RT01.4- I've Got a Bone to Pick with You - CF Bone Disease

Location: 345 - 346

Facilitator: – MHealth Fairview, Minneapolis, MN

PHARM

12:30 PM - 2:00 PM PDT

RT01.5- Finding Waze Around the Traffic: Motility Medications Management

Location: 345 - 346

Facilitator: – Samford University McWhorter School of Pharmacy

PHARM

12:30 PM - 2:00 PM PDT

RT01.14- Plant Based Diets in CF

Location: 345 - 346

Facilitator: – Children's Hospital at Erlanger

PHARM

12:30 PM - 2:00 PM PDT

RT01.7- Come DeepSeek & ChatGPT with Me: Utilizing AI to Improve Efficiency

Location: 345 - 346

Facilitator: – Children's Wisconsin

PHARM

12:30 PM - 2:00 PM PDT

RT01.8- Rebalancing the Checkbook: Sustaining Pharmacy Services with Reduced Modulator Revenue

Location: 345 - 346

Facilitator: – Primary Children's Cystic Fibrosis Clinic

PHARM

12:30 PM - 2:00 PM PDT

RT01.9- CF 101 for New Pediatric Psychosocial Clinicians

Location: 345 - 346

Facilitator: – University of Colorado SOM/Children's Hospital Colorado

SW/PSYCH

12:30 PM - 2:00 PM PDT

RT01.10- Child Life Specialist Networking

Location: 345 - 346

Facilitator: – Seattle Children's Hospital

SW/PSYCH

12:30 PM - 2:00 PM PDT

RT01.11- CF 101 for New Adult Psychosocial Clinicians

Location: 345 - 346

Facilitator: – UVAHealth Adult Cystic Fibrosis Clinic

SW/PSYCH

12:30 PM - 2:00 PM PDT

RT01.12- Navigating Perinatal Mental Health

Location: 345 - 346

Facilitator: – Inova Fairfax

SW/PSYCH

12:30 PM - 2:00 PM PDT

RT01.13- School Concerns & Accommodations

Location: 345 - 346

Facilitator: – Children's Mercy Kansas City

SW/PSYCH

12:30 PM - 2:00 PM PDT

RT01.14- Plant Based Diets in CF

Location: 345 - 346

Facilitator: – M Health Fairview University of Minnesota Medical Center

NTR

12:30 PM - 2:00 PM PDT

RT01.15- CF Nutrition Meal Prep/Planning

Location: 345 - 346

Facilitator: – Boston Children's Health Physicians

NTR

12:30 PM - 2:00 PM PDT

RT01.16- Nutrition Care of Transgender Patients

Location: 345 - 346

Facilitator: – Rady Children's Hospital - San Diego

NTR

12:30 PM - 2:00 PM PDT

RT01.17- Adult Nutrition 101

Location: 345 - 346

Facilitator: – University of Utah Adult CF Team

NTR

12:30 PM - 2:00 PM PDT

Roundtables: Group 2

Location: Elliott Bay

12:30 PM - 2:00 PM PDT

RT02.1- Anyone Can Lead

Location: Elliott Bay

Facilitator: – Seattle Children's Hospital

CLIN

12:30 PM - 2:00 PM PDT

RT02.2- Preparing Patients for Lung Transplant: Patient Education

Location: Elliott Bay

Facilitator:

CLIN

12:30 PM - 2:00 PM PDT

RT02.3- Pre-Screening Visit Setup Example

Location: Elliott Bay

Facilitator: – PennState Health/PennState College of Medicine

CLIN

12:30 PM - 2:00 PM PDT

RT02.4- Practical CGM: Choosing, Obtaining, & Placing a Sensor

Location: Elliott Bay

Facilitator: – Stanford University

CLIN

12:30 PM - 2:00 PM PDT

RT02.5- Obtaining CGM Coverage for People with CFRD

Location: Elliott Bay

Facilitator:

CLIN

12:30 PM - 2:00 PM PDT

RT02.6- Abnormal Glucose Tolerance

Location: Elliott Bay

Facilitator: – Nationwide Children's Hospital

CLIN

12:30 PM - 2:00 PM PDT

RT02.7- Unraveling the Mystery of Elevated Liver & HEMT: Is This DILI?

Location: Elliott Bay

Facilitator: – University of Colorado SOM and Children's Hospital Colorado

CLIN

12:30 PM - 2:00 PM PDT

RT02.8- Rethinking Acid Balance in CF

Location: Elliott Bay

Facilitator: – University of Florida

CLIN

12:30 PM - 2:00 PM PDT

RT02.9- When the Gut Gets Stuck: Distinguishing & Managing Constipation vs. DIOS

Location: Elliott Bay

Facilitator:

CLIN

12:30 PM - 2:00 PM PDT

RT02.10- CRMS & CFTR Dysfunction: Unraveling GI Symptoms & Effective Management

Location: Elliott Bay

Facilitator: – Hadassah Medical Center

CLIN

12:30 PM - 2:00 PM PDT

RT02.11- Measurements of CFTR Function

Location: Elliott Bay

Facilitator: – CFFT Lab, Cystic Fibrosis Foundation, Lexington, MA, USA

PTAC/CFTR

12:30 PM - 2:00 PM PDT

RT02.12- Strategies to Improve Partnership with the CF Hispanic Community

Location: Elliott Bay

Facilitator: – University of Texas Health San Antonio

HEAC

12:30 PM - 2:00 PM PDT

Roundtables: Group 3

Location: 447 - 448

12:30 PM - 2:00 PM PDT

RT03.1- Movement Matters: Navigating Developmental Concerns in Pediatric

Location: 447 - 448

Facilitator: – Childrens Nebraska

PT&RT

12:30 PM - 2:00 PM PDT

RT03.2- Every Breath You take: Utilizing Inspiratory/Respiratory Muscle Training in CF

Location: 447 - 448

Facilitator: – Johns Hopkins Hospital

PT&RT

12:30 PM - 2:00 PM PDT

RT03.3- Knack Three Times; Addressing Pelvic Floor Issues

Location: 447 - 448

Facilitator: – Boston Children's Hospital

PT&RT

12:30 PM - 2:00 PM PDT

RT03.4- Take 2 Steps Forward-Using the A-Step in Clinic

Location: 447 - 448

Facilitator: – Johns Hopkins Hospital - Children's Center

PT&RT

12:30 PM - 2:00 PM PDT

RT03.5- Staying Afloat: Strategies for Sustainable CF PT Services

Location: 447 - 448

Facilitator: – Pediatric Pulmonology, C.S Mott Children's Hospital, University of Michigan Health

PT&RT

12:30 PM - 2:00 PM PDT

RT03.6- PT & RT Impact: Measuring What Matters Using QI projects

Location: 447 - 448

Facilitator: – Johns Hopkins Hospital

PT&RT

12:30 PM - 2:00 PM PDT

RT03.7- Providing CF Care to Military Families

Location: 447 - 448

Facilitator: – Naval Medical Center Portsmouth

PT&RT

12:30 PM - 2:00 PM PDT

RT03.8- Baby Bump-Discussing Pregnancy Related Issues for the Mom with CF

Location: 447 - 448

Facilitator: – Maine Medical Center

PT&RT

12:30 PM - 2:00 PM PDT

RT03.9- Succession Planning

Location: 447 - 448

Facilitator: – Adult CF Center of Central Texas

PT&RT

12:30 PM - 2:00 PM PDT

RT03.10- Sweat Testing

Location: 447 - 448

Facilitator: – Rady Children's Hospital San Diego

PT&RT

12:30 PM - 2:00 PM PDT

RT03.11- Interpretation of Clinic Spirometry for CF Nurses

Location: 447 - 448

Facilitator: – Stanford University

NRS

12:30 PM - 2:00 PM PDT

RT03.12- CF Registry/Next Gen Registry

Location: 447 - 448

Facilitator: – Adult CF Center at University of Utah Health

NRS

12:30 PM - 2:00 PM PDT

RT03.13- Incorporating QI Into CF Clinic

Location: 447 - 448

Facilitator: – UNM

NRS

12:30 PM - 2:00 PM PDT

RT03.14- Transition Strategies

Location: 447 - 448

Facilitator: – UVA Pediatric Cystic Fibrosis Program

NRS

12:30 PM - 2:00 PM PDT

RT03.15- Improving QNS Rates for Sweat Testing

Location: 447 - 448

Facilitator:

NRS

12:30 PM - 2:00 PM PDT

RT03.16- Genetic Variant Websites for the CF Clinic Nurse

Location: 447 - 448

Facilitator: – Medical University of South Carolina

NRS

12:30 PM - 2:00 PM PDT

TPS02--Models Systems to Study Pulmonary & Non-pulmonary Manifestations of CF

Location: Theater A Exhibit Hall

Chair: – Cleveland Clinic

Chair: – The Ohio State University Wexner Medical Center

IMI

12:30 PM - 2:00 PM PDT

A CFTR mouse model to study nonsense mutations independent of nonsense-mediated decay.

Location: Theater A Exhibit Hall

Speaker: – Case Western Reserve University.

12:30 PM - 2:00 PM PDT

Modeling cystic fibrosis patient-specific responses to modulators using human induced pluripotent stem cells

Location: Theater A Exhibit Hall

Speaker: – University of Toronto & The Hospital for Sick Children

12:30 PM - 2:00 PM PDT

Nitric oxide-releasing prodrug eradicates Pseudomonas aeruginosa and reduces inflammation in a mucus-producing rat model for cystic fibrosis

Location: Theater A Exhibit Hall

Speaker: – University of North Carolina at Chapel Hill

12:30 PM - 2:00 PM PDT

ETI treatment extends the lifespan of CFTR-F508del rabbits

Location: Theater A Exhibit Hall

Speaker: – University of Michigan

12:30 PM - 2:00 PM PDT

Increased small airway clearance after starting highly effective modulator therapy: Decoding "the purge" in cystic fibrosis

Location: Theater A Exhibit Hall

Speaker: – University of Iowa

12:30 PM - 2:00 PM PDT

Efficient mRNA delivery to the ferret lung using Selectivity Enabling Nanoshell (SENS™)

Location: Theater A Exhibit Hall

Speaker: – University of Iowa

12:30 PM - 2:00 PM PDT

Cystic Fibrosis-related neurodegenerative disease associated with tauopathy and cognitive decline in aged CF mice

Location: Theater A Exhibit Hall

Speaker: – Case Western Reserve University

12:30 PM - 2:00 PM PDT

Development of iPSC reporter lines to track ionocyte specification and maturation

Location: Theater A Exhibit Hall

Speaker:

12:30 PM - 2:00 PM PDT

iPSC-derived human intestinal organoids model gastrointestinal manifestations of Cystic Fibrosis

Location: Theater A Exhibit Hall

Speaker: – University of North Carolina at Chapel Hill

12:30 PM - 2:00 PM PDT

Understanding the role of CFTR in pancreatic progenitor development to target exocrine pancreatic insufficiency

Location: Theater A Exhibit Hall

Speaker: – University of Iowa

1:00 PM - 2:30 PM PDT

CF Foundation Grants Administration Insights: Applications, Funding, and Reporting Demystified

Location: 340-342

Chair: – Cystic Fibrosis Foundation

1:30 PM - 2:20 PM PDT

FSC03--A Conversation with Antoinette Gardner

Location: Fireside Chat A Exhibit Hall

Speaker: – LSU Health Shreveport

Facilitator: – Cohen Children's Medical Center

NRS

1:30 PM - 2:20 PM PDT

FSC04--A Conversation with Meghana Sathe & Melissa Putman

Location: Fireside Chat B Exhibit Hall

Speaker: – Pediatric Gastroenterology and Nutrition, University of Texas Southwestern/Children's Medical Center of Dallas, Dallas, TX, US

Speaker: – Massachusetts General Hospita

Facilitator: – Case Western Reserve University

CLIN

1:30 PM - 2:20 PM PDT

RFPT04--Psychosocial Research

Location: Theater B Exhibit Hall

Chair: – St. Luke's Cystic Fibrosis Center of Idaho

Chair: – Cook Children's

SW/PSYCH

1:30 PM - 2:20 PM PDT

RFPT05--New Ways to Combat CF Pathogens

Location: Theater B Exhibit Hall

Chair: – University of California Irvine

Chair:

IMI

2:30 PM - 4:00 PM PDT

TPS03--Imaging: The Final Frontier

Location: Theater A Exhibit Hall

Chair: – University of British Columbia

Chair: – Childrens Hospital Colorado and University of Colorado

CLIN

2:30 PM - 4:00 PM PDT

Changes in lung function and lung ventilation following commencement of Elexacaftor - Tezacaftor - Ivacaftor in a ≤6 year old cohort

Location: Theater A Exhibit Hall

Speaker: – University of Adelaide / Women's and Children's Hospital

2:30 PM - 4:00 PM PDT

Quantitative CT scoring of mucus plugs in people with Cystic Fibrosis

Location: Theater A Exhibit Hall

Speaker:

2:30 PM - 4:00 PM PDT

Structural lung abnormalities in children and adults with cystic fibrosis after ETI using AI automated algorithms

Location: Theater A Exhibit Hall

Speaker: – Erasmus MC - Sophia Children's Hospital

2:30 PM - 4:00 PM PDT

Elexacaftor/Tezacaftor/Ivacaftor is associated with improvements in mucus plugging, air trapping and bronchial thickening but not bronchial widening in people with CF aged 12 years and older

Location: Theater A Exhibit Hall

Speaker: – RCSI University of Medicine and Health Sciences

2:30 PM - 4:00 PM PDT

Olfactory function and sinonasal opacification improve in young children with cystic fibrosis treated with elexacaftor/tezacaftor/ivacator (ETI)

Location: Theater A Exhibit Hall

Speaker: – David Geffen School of Medicine at UCLA

2:30 PM - 4:00 PM PDT

Assessment of lung disease in people with cystic fibrosis using electrical impedance tomography

Location: Theater A Exhibit Hall

Speaker: – Children's Hospital of Philadelphia

2:30 PM - 4:00 PM PDT

Effect of inhaled dry-powder mannitol on mucociliary clearance in moderate to severe CF lung disease while using elexacaftor/tezacaftor/ivacaftor

Location: Theater A Exhibit Hall

Speaker: – University of North Carolina at Chapel Hill

2:30 PM - 4:00 PM PDT

Elexacaftor-Tezacaftor-Ivacaftor reduces bronchial dilatations in adolescents with Cystic Fibrosis

Location: Theater A Exhibit Hall

Speaker: – INSERM

2:30 PM - 4:00 PM PDT

Do CT images accurately identify inflammatory ‘hotspots’ in the CF lung

Location: Theater A Exhibit Hall

Speaker:

2:30 PM - 4:00 PM PDT

Body fat distribution impacts glucose and insulin secretory indices in people with cystic fibrosis

Location: Theater A Exhibit Hall

Speaker: – Emory University

2:30 PM - 4:30 PM PDT

S01--Tips & Tricks for Running an Efficient Multidisciplinary CF Clinic

Location: 420-422

Chair: – Helen DeVos Children's Hospital

Chair: – University of Arkansas for Medical Sciences

NRS

2:30 PM - 4:30 PM PDT

S01.1- Clinic Magic Starts Before the Visit

Location: 420-422

Speaker: – Children's Hospital Los Angeles

2:30 PM - 4:30 PM PDT

S01.2- From Old School to New School: An Electronic Approach to CF Clinic Workflow

Location: 420-422

Speaker: – Helen DeVos Children's Hospital CF Care Center

2:30 PM - 4:30 PM PDT

S01.3- Who Has Time for QI? (Spoiler, You Do!)

Location: 420-422

Speaker: – Adult CF Center of Central Texas

2:30 PM - 4:30 PM PDT

S01.4- Teamwork is the Best Kind of Work: Team Strategies to Implement During Clinic to Improve Clinic Flow

Location: 420-422

Speaker: – Nebraska Medicine

2:30 PM - 4:30 PM PDT

S02--Uncharted Territory: Exploring Metabolic Dysfunction in the Post-HEM Era

Location: Signature Room

Chair: – Northwestern Medicine

Chair: – Banner Health

PHARM

2:30 PM - 4:30 PM PDT

S02.1- Optimizing Nutritional Status in CF: The Non-Pharmacological Route

Location: Signature Room

Speaker: – Northwestern Memorial Hospital

2:30 PM - 4:30 PM PDT

S02.2- GLP1 Receptor Agonists in CF? I've Got a Gut Feeling About This

Location: Signature Room

Speaker: – Mayo Clinic

2:30 PM - 4:30 PM PDT

S02.3- Hyperlipidemia Hibachi: Turning Up the Heat on Cholesterol Management in CF

Location: Signature Room

Speaker: – University of Rochester Medical Center

2:30 PM - 4:30 PM PDT

S02.4- Tech to Tablets: Screening and Management of CFRD

Location: Signature Room

Speaker: – Seattle Children's Hospital

2:30 PM - 4:30 PM PDT

S03--The Need for Comprehensive CF Care to be "Ageless"

Location: Flex A

Chair: – UAB Division of Pediatrics

Chair: – University of Pennsylvania

CLIN

2:30 PM - 4:30 PM PDT

S03.1- CF Care Center Role in Primary Care

Location: Flex A

Speaker: – Univ. of Washington

2:30 PM - 4:30 PM PDT

S03.2- Emerging Issues in Caring for Adolescents and Young Adults with CF

Location: Flex A

Speaker: – University of Pittsburgh

2:30 PM - 4:30 PM PDT

S03.3- Cardiovascular Risk Reduction in PwCF

Location: Flex A

Speaker: – University of Washington Medical Center

2:30 PM - 4:30 PM PDT

S03.4- Cancer Screening - Adolescents and Beyond

Location: Flex A

Speaker: – St. Michael's Hospital, Unity Health Toronto

2:30 PM - 4:30 PM PDT

S04--Growing Up is Getting Old

Location: 431-432

Chair: – University of Minnesota Cystic Fibrosis Center

Chair: – Royal Brompton Hospital, Guys and St Thomas's NHS Foundation Trust and NHLI, Imperial College, London

PT&RT

2:30 PM - 4:30 PM PDT

S04.1- Breathing Through the Years: CF and the Aging Lung

Location: 431-432

Speaker: – Royal Brompton Hospital, Guys and St Thomas's NHS Foundation Trust and NHLI, Imperial College, London

2:30 PM - 4:30 PM PDT

S04.2- Acquiring the Mental Health Tools to Age Gracefully with CF

Location: 431-432

Speaker: – Johns Hopkins Hospital

2:30 PM - 4:30 PM PDT

S04.3- Built to Last: Supporting Function in the Aging CF Population

Location: 431-432

Speaker: – University of Southern California

2:30 PM - 4:30 PM PDT

S04.4- Loving Life - Breathlessly

Location: 431-432

Community Speaker: – John's Hopkins CF Clinic

2:30 PM - 4:30 PM PDT

S05.1- Rescuing CFTR to treat conventional CF: when, where and how much?

Location: 423-425

Speaker: – Charité - Universitätsmedizin Berlin

2:30 PM - 4:30 PM PDT

S05.2- CFTR mutations with incomplete penetrance: CRMS and CF-SPID

Location: 423-425

Speaker: – INSERM

2:30 PM - 4:30 PM PDT

S05.3- Functional inhibition of wild-type CFTR: role in COPD and other chronic diseases

Location: 423-425

Speaker: – UAB

2:30 PM - 4:30 PM PDT

S05.4- The CF carrier advantage: were CFTR mutations selected along human evolution and why

Location: 423-425

Speaker: – Department of Pediatrics, Emory University

2:30 PM - 4:30 PM PDT

S05--Along the CFTR Spectrum: CF Off/On Modulators, CRMS/CF-SPID, COPD & CF Carriers

Location: 423-425

Chair: – Case Western Reserve University

Chair: – Departments of Pediatrics and Population Health Sciences, University of Wisconsin School of Medicine and Public Health

APPTTPTAC/CFTRCLIN

2:30 PM - 4:30 PM PDT

S06--Cure (or Close) for All

Location: 435

Chair: – Emory University

Chair: – Seattle Children's Hospital

Community Chair: – Realistic Expectations PLLC

HEACSW/PSYCHCLIN

2:30 PM - 4:30 PM PDT

S06.1- Michelle Patovani’s story

Location: 435

Community Speaker: – CFF

2:30 PM - 4:30 PM PDT

S06.2- Economic Divides, Shared Struggles: International access

Location: 435

Speaker: – Imperial College London

2:30 PM - 4:30 PM PDT

S06.3- Cost/insurance issues to access for all: ethics of high pricing

Location: 435

Speaker:

2:30 PM - 4:30 PM PDT

S06.4- Community engagement and partnerships in research (Feature PRIDE CF)

Location: 435

Speaker: – University of Pittsburgh

2:30 PM - 4:30 PM PDT

S07--Game of Thrones: Inflammation Initiators & Drivers Across the Lifespan

Location: 433-434

Chair: – Tulane University School of Medicine

Chair: – University of Iowa

IMI

2:30 PM - 4:30 PM PDT

S07.1- Initiation: Chicken and Egg (Infection and Inflammation)

Location: 433-434

Speaker: – TU Munich

2:30 PM - 4:30 PM PDT

S07.2- Nightwatch at the Mucosal Wall: A Tale of Host-Pathogen Dynamics

Location: 433-434

Speaker: – University of Alabama at Birmingham

2:30 PM - 4:30 PM PDT

S07.3- Immune Targets for Therapies: What is Essential for Host Defense? What is Deleterious?

Location: 433-434

Speaker: – Yale University School of Medicine

2:30 PM - 4:30 PM PDT

S07.4- Disease variability: sex and mutation and heterogeneity

Location: 433-434

Speaker: – Yale University

2:30 PM - 4:30 PM PDT

S08--Rethinking Pulmonary Management in the Current Era of CF

Location: Ballroom 2

Chair: – Riley Hospital for Children at Indiana University Health

Chair: – Children's Hospital of Philadelphia, Division of Pulmonary and Sleep Medicine

CLIN

2:30 PM - 4:30 PM PDT

S08.1- Patient Perspective

Location: Ballroom 2

Speaker:

2:30 PM - 4:30 PM PDT

S08.2- Management of Pulmonary Exacerbations in the Post ETI Era

Location: Ballroom 2

Speaker:

2:30 PM - 4:30 PM PDT

S08.3- Changes in Pulmonary Exacerbations in Children with CF

Location: Ballroom 2

Speaker: – Children's Hospital of Richmond at Virginia Commonwealth Unversity

2:30 PM - 4:30 PM PDT

S08.4- HERO-2: Decentralized Trials to Study De-escalation

Location: Ballroom 2

Speaker: – Children's Hospital of Philadelphia

2:30 PM - 4:30 PM PDT

S09--CF Therapeutics When There is No Protein Made

Location: Terrace Suite

Chair: – Department of Genetic Medicine, Johns Hopkins University School of Medicine

Chair: – University of Rochester School of Medicine and Dentistry

PTAC/CFTR

2:30 PM - 4:30 PM PDT

S09.1- Timing is everything: kinetic studies of nonsense-mediated mRNA decay

Location: Terrace Suite

Speaker: – National Heart, Lung, and Blood Institute

2:30 PM - 4:30 PM PDT

S09.2- ASO therapies when protein is not made

Location: Terrace Suite

Speaker: – Hebrew University

2:30 PM - 4:30 PM PDT

S09.3- Readthrough of CFTR nonsense codons by R-ASOs

Location: Terrace Suite

Speaker: – University of Massachusetts Chan Medical School

2:30 PM - 4:30 PM PDT

S09.4- Strategies to replace the full-length CFTR cDNA in airway stem cells

Location: Terrace Suite

Speaker: – Nationwide Children's Hospital

2:30 PM - 4:30 PM PDT

S10--Pancreatic Puzzles & Nutrition Noodles: Untangling Modulator Nutrition Challenges

Location: 427-429

Chair: – Alfred Health

Chair: – University of New South Wales & Sydney Children's Hospital

NTR

2:30 PM - 4:30 PM PDT

S10.1- Measurement of Pancreatic Status: Fecal Elastase and Beyond

Location: 427-429

Speaker: – Cleveland Clinic Children's Hospital

2:30 PM - 4:30 PM PDT

S10.2- Update on CF Gut Microbiome

Location: 427-429

Speaker: – University of New South Wales & Sydney Children's Hospital

2:30 PM - 4:30 PM PDT

S10.3- CF Liver Disease in the Setting of Modulators: Special Focus on Metabolic Dysfunction-associated Fatty Liver Disease (MAFLD)

Location: 427-429

Speaker: – UTSW (University of Texas Southwestern)

2:30 PM - 4:30 PM PDT

S10.4- Simplifying Nutrition Interventions in the Setting of HEMT: When and How Do We Do This?

Location: 427-429

Speaker: – School of Clinical Medicine, Discipline of Paediatrics & Child Health, UNSW Medicine & Health, University of New South Wales, Australia

2:30 PM - 4:30 PM PDT

S11--Mental Health Year in Review: Presented by MHAC & PRIME

Location: Ballroom 1

Chair: – Joe DiMaggio Cystic Fibrosis Center

Chair: – University of Florida

SW/PSYCH

2:30 PM - 4:30 PM PDT

S11.1- Evaluation of Professional Quality of Life and Prevalence of Burnout: A National Survey of Healthcare Providers on Cystic Fibrosis Care Teams

Location: Ballroom 1

Speaker: – Joe DiMaggio Cystic Fibrosis Center

2:30 PM - 4:30 PM PDT

S11.2- Treating Mental Health Symptoms in People with CF: How a Systematic Review Can Inform Clinical Practice

Location: Ballroom 1

Speaker: – University of Colorado SOM/Children's Hospital Colorado

2:30 PM - 4:30 PM PDT

S11.3- From Inflammation to Emotion: Basic Science Perspectives on Mental and Physical Health

Location: Ballroom 1

Speaker: – University of Florida

2:30 PM - 4:30 PM PDT

S11.4- Restarting Triple Therapy with Robust Monitoring for Adverse Events

Location: Ballroom 1

Speaker: – National Jewish Health

2:30 PM - 4:30 PM PDT

S12--PRenatal MOdulator Treatment to PrEvent CF ComplicaTions (PROTECT)

Location: Ballroom 3

Chair: – Medical University of South Carolina

Chair: – University of Pennsylvania Perelman School of Medicine

CLIN

2:30 PM - 4:30 PM PDT

S12.1- “I Don’t Have CF but My Baby Does”: Experiences of Parents without CF Who Used CFTR Modulators During Pregnancy or Breastfeeding

Location: Ballroom 3

Speaker: – Living Roots Counseling

Speaker: – N/A

2:30 PM - 4:30 PM PDT

S12.3- Effects of Highly Effective Modulator Therapy on CF Ferret Fertility and Pregnancy

Location: Ballroom 3

Speaker: – University of Alabama at Birmingham

2:30 PM - 4:30 PM PDT

S12.3- Safety of CFTR modulators in healthy controls and pregnant people with CF

Location: Ballroom 3

Speaker: – Jennifer L. Taylor-Cousar, MD, MSCS, ATSF

2:30 PM - 4:30 PM PDT

S12.4- Summary of US & European Case Studies: Fetal Treatment via CF Carrier Mothers

Location: Ballroom 3

Speaker: – Medical University of South Carolina

5:00 PM - 6:30 PM PDT

PL1--Six Years of Highly Effective Modulator Therapy and Beyond: Reflecting Back & Looking Forward

Location: Flex C

Speaker: – Columbia University Irving Medical Center

Speaker: – Charité - Universitätsmedizin Berlin

6:00 AM - 6:30 PM PDT

Registration Open

Location: Summit Lobby

7:45 AM - 9:45 AM PDT

AF1- Screening for CF Among Our Patients with Bronchiectasis: An Unmet Need

Location: Ballroom 1

Speaker: – Columbia University Medical Center

7:45 AM - 9:45 AM PDT

AF2- Beyond Infection and Inflammation: Malignancy in the Differential for Chest CT Abnormalities in Cystic Fibrosis.

Location: Ballroom 1

Speaker:

7:45 AM - 9:45 AM PDT

AF3- Gastrointestinal malignancy: Risk stratification and screening in people with cystic fibrosis

Location: Ballroom 1

Speaker: – University of Minnesota

7:45 AM - 9:45 AM PDT

AF4- Recurrent abdominal pain in a cystic fibrosis patient with a history of non-tuberculous mycobacterial pulmonary disease.

Location: Ballroom 1

Speaker: – Brigham and Women's Hospital

7:45 AM - 9:45 AM PDT

AF5- Recurrent Pancreatitis in a CFTR Heterozygote: Clinical Response to CFTR Modulator Therapy and Discordant Biomarker Response

Location: Ballroom 1

Speaker:

7:45 AM - 9:45 AM PDT

AF6- Endothelial dysfunction in Cystic Fibrosis

Location: Ballroom 1

Speaker:

7:45 AM - 9:45 AM PDT

AF7- Administration of elexacaftor/tezacaftor/ivacaftor in a CFTR carrier mother for treatment of meconium ileus in a F508del fetus with extension of therapy into the postpartum period

Location: Ballroom 1

Speaker:

7:45 AM - 9:45 AM PDT

AF--Adult Fellows

Location: Ballroom 1

Chair: – Johns Hopkins University

Chair: – University of Pittsburgh

Facilitator:

CLIN

7:45 AM - 9:45 AM PDT

PF1- The comeback kid: Pulmonary and pancreatic restoration in a school-aged child with cystic fibrosis on long-term highly effective modulator therapy

Location: Flex A

Speaker:

7:45 AM - 9:45 AM PDT

PF2- What’s all the rash about? A case of suspected cystic fibrosis dermatitis arthritis syndrome (CF-DAS) in a pediatric patient

Location: Flex A

Speaker: – Ann & Robert H. Lurie Children's Hospital of Chicago, McGaw Medical Center of Northwestern University

7:45 AM - 9:45 AM PDT

PF3- Constipation or Complication: When to think outside the box

Location: Flex A

Speaker:

7:45 AM - 9:45 AM PDT

PF4- ETI and the styes

Location: Flex A

Speaker:

7:45 AM - 9:45 AM PDT

PF5- A pediatric patient with cystic fibrosis (F508del/3659delC) with persistently elevated sweat chloride levels despite elexacaftor-tezacaftor-ivacaftor therapy

Location: Flex A

Speaker: – Nationwide Children's Hospital

7:45 AM - 9:45 AM PDT

PF6- ‘Fungal disease; not just an innocent bystander in Cystic Fibrosis’

Location: Flex A

Speaker:

7:45 AM - 9:45 AM PDT

PF7- A case of recurrent massive hemoptysis and bronchiectasis in a toddler with cystic fibrosis treated with bronchial artery embolization and lobectomy

Location: Flex A

Speaker: – UPMC Children's Hospital of Pittsburgh

7:45 AM - 9:45 AM PDT

PF--Pediatric Fellows

Location: Flex A

Chair:

Chair: – The Hospital for Sick Children

Facilitator:

CLIN

7:45 AM - 9:45 AM PDT

W16--Host Response to CF Airway Infections

Location: Signature Room

Chair: – McGIll University

Chair: – Rutgers New Jersey Medical School

IMI

7:45 AM - 9:45 AM PDT

W16.1- Hidden in plain sight: Rediscovering Mast Cells in Cystic Fibrosis

Location: Signature Room

Speaker: – Emory University

7:45 AM - 9:45 AM PDT

W16.2- CFTR modulator impact on naive T cell programming

Location: Signature Room

Speaker: – National Jewish Health

7:45 AM - 9:45 AM PDT

W16.3- Evolution and pathoadaptation of Pseudomonas aeruginosa through the gut-lung axis in cystic fibrosis

Location: Signature Room

Speaker: – Dartmouth College

7:45 AM - 9:45 AM PDT

W16.4- Displacement of methicillin-resistant Staphylococcus aureus following ETI treatment for CF.

Location: Signature Room

Speaker: – University of Iowa

7:45 AM - 9:45 AM PDT

W16.5- Tracking Pseudomonas aeruginosa adaptation under CFTR modulator therapy: a longitudinal multi-omics study

Location: Signature Room

Speaker: – Infections and Cystic Fibrosis Unit, San Raffaele Scientific Institute

7:45 AM - 9:45 AM PDT

W17--Extrapulmonary Manifestations & Mechanisms

Location: 427-429

Chair: – Case Western Reserve University

Chair: – University of Virginia

EPPPTAC/CFTR

7:45 AM - 9:45 AM PDT

W17.1- Neurological outcomes of in-utero treatment with ETI

Location: 427-429

Speaker: – Case Western Reserve University

7:45 AM - 9:45 AM PDT

W17.2- Disruption of hippocampal function by ETI therapy

Location: 427-429

Speaker:

7:45 AM - 9:45 AM PDT

W17.3- Antigen-experienced CD4+ T cell clonal expansion characterizes CF-related diabetes

Location: 427-429

Speaker: – University of Alabama at Birmingham

7:45 AM - 9:45 AM PDT

W17.4- Absent CFTR function is associated with progressive kidney injury and abnormal mineral metabolism in an in vivo mouse model

Location: 427-429

Speaker: – University of Virginia

7:45 AM - 9:45 AM PDT

W17.5- Leaky gut, dysbiosis, and inflammation support inter-organ communication in Cystic Fibrosis

Location: 427-429

Speaker: – San Raffaele Scientific Institute

7:45 AM - 9:45 AM PDT

DG13--Double Take: Challenging CF Cases Worth Another Look

Location: 320-322

Chair: – Intermountain Health

Chair: – Nebraska Regional Pediatric CF Center

Speaker: – University of Utah Health

Speaker: – Yale New Haven Health

Speaker: – Northwell Health

Speaker: – Primary Children's Hospital

PHARM

7:45 AM - 9:45 AM PDT

DG14--Delivering CF Care in Low & Middle Income Countries

Location: 343-344

Chair: – University of Michigan Health

Chair: – Children's of Alabama

Community Speaker:

Speaker: – University of Michigan Health

Speaker: – Stanford Children's Hospital

Speaker: – Hospital Dr. H. Notti

Speaker: – UAB Department of Pediatrics

NRS

7:45 AM - 9:45 AM PDT

DG15--A New Spin on Classic CF Nutrition Care

Location: 331-332

Chair: – Johns Hopkins Hospital

Chair: – Corewell Health

Speaker: – Children's Hospital of Philadelphia

Speaker: – Primary Children's Hospital

Speaker: – Medical University of South Carolina

Community Speaker: – Corewell Health

NTR

7:45 AM - 9:45 AM PDT

DG16--APP Grand Rounds- Enhancing Lives Through Expertise: The Integral Role of Advanced Practice Providers in CF Care

Location: 343-346

Chair: – Baylor College of Medicine

Chair: – Akron Children's

Speaker:

NRS

7:45 AM - 9:45 AM PDT

DG17--Seeing More Than CF 3.0

Location: 340-342

Chair: – Childrens Hospital of Alabama

Chair: – Nemours Children's Hospital~Delaware

Speaker: – Massachusetts General Hospital/Harvard Medical School

Speaker: – Washington University School of Medicine

Speaker: – Children's Hospital of Philadelphia

Speaker: – The Hospital for Sick Children

PT&RT

7:45 AM - 9:45 AM PDT

DG18--Psychology/Psychiatry Networking & Knowledge

Location: 335-336

Chair: – UNC Medical Center

Chair: – Nemours Children's Health

Speaker: – Jacobs School of Medicine and Biomedical Sciences, University at Buffalo

Speaker: – Cincinnati Children's Hospital Medical Center, Divisions of Behavioral Medicine and Clinical Psychology & Pulmonary Medicine

Speaker: – Medical University of South Carolina

SW/PSYCH

7:45 AM - 9:45 AM PDT

DG19--Everything You Ever Wanted to Know (& more!) About CFTR Variant Interpretation

Location: 447-448

Chair: – Mayo Clinic

Chair: – Ann & Robert H. Lurie Children's Hospital of Chicago

Speaker: – Ann & Robert H. Lurie Children's Hospital of Chicago

CLIN

7:45 AM - 9:45 AM PDT

DG20--It's Important to be Dense: Nutrition & Exercise to Improve Bone Density & Working with Other Endocrine Issues

Location: 347-348

Chair: – Primary Children's Hospital

Chair: – Adult Cystic Fibrosis Center of Central Texas

Speaker: – Dell Children's Medical Center of Central Texas

Speaker: – Medical University of South Carolina

Speaker: – UTSW

PT&RT

7:45 AM - 9:45 AM PDT

DG21--Social Work Networking & Knowledge

Location: 333-334

Chair: – Children's Hospital of Michigan

Chair: – Nemours Children's Health - Orlando

Speaker: – BreatheStrong CF

Speaker: – Cystic Fibrosis Foundation

Speaker: – The Bonnell Foundation: Living with cystic fibrosis

SW/PSYCH

7:45 AM - 9:45 AM PDT

DG22--Tech in Research

Location: 327-329

Chair: – National Jewish Health

Chair: – Boston Children's Hospital

Chair: – University of Pittsburgh

Speaker: – UNC-Chapel Hill

Speaker: – University of North Carolina at Chapel Hill

Speaker: – West Virginia University Department of Pediatrics

Speaker:

CLIN

9:00 AM - 9:50 AM PDT

RFPT06--New Advances in Stem Cell Biology

Location: Theater B Exhibit Hall

Chair: – University of Alabama at Birmingham

Chair: – Boston University/Boston Medical Center

PTAC/CFTRAPPTT

9:00 AM - 9:50 AM PDT

RFPT07--Topics Related to Health Equity, Cost, Access, & International Issues

Location: Theater B Exhibit Hall

Chair: – UCLA

Chair: – University of Washington

HEACSW/PSYCH

9:00 AM - 11:00 AM PDT

Coffee Break

9:00 AM - 5:00 PM PDT

Exhibit & Poster Hall Open

10:15 AM - 11:45 AM PDT

TPS04--Lungs & Beyond

Location: Theater A Exhibit Hall

Chair: – University of Alabama-Birmingham

Chair: – National Jewish Health

CLIN

10:15 AM - 11:45 AM PDT

Impact of highly effective modulator therapy on chronic rhinosinusitis and olfactory dysfunction: 4-year outcomes

Location: Theater A Exhibit Hall

Speaker: – University of Michigan Medical School

10:15 AM - 11:45 AM PDT

Decreased elexacaftor/tezacaftor/ivacaftor concentrations during pregnancy: the MAYFLOWERS PK Sub-study

Location: Theater A Exhibit Hall

Speaker: – Univ of North Carolina Chapel

10:15 AM - 11:45 AM PDT

Pancreatic cancer risk in adults living longer with CF: Early insights from an MRCP-based screening protocol

Location: Theater A Exhibit Hall

Speaker: – Brigham and Women's Hospital and Boston Children's Hospital

10:15 AM - 11:45 AM PDT

The power of breath: An innovative diagnostic for P. aeruginosa cystic fibrosis lung infections

Location: Theater A Exhibit Hall

Speaker: – Arizona State University

10:15 AM - 11:45 AM PDT

Impact of elexacaftor, tezacaftor and ivacaftor on hepatic status after 4-5 years: Results of the combined PROMISE and RECOVER studies.

Location: Theater A Exhibit Hall

Speaker: – University of Colorado SOM and Children's Hospital Colorado

10:15 AM - 11:45 AM PDT

Proteomic analysis of exhaled breath condensate to identify protein signatures of infection in people with cystic fibrosis

Location: Theater A Exhibit Hall

Speaker: – University of Kansas Medical Center

10:15 AM - 11:45 AM PDT

Outcomes in first year of life for infants with exposure to elexacaftor/tezacaftor/ivacaftor (ETI) in utero

Location: Theater A Exhibit Hall

Speaker: – Johns Hopkins All Children's Hospital

10:15 AM - 11:45 AM PDT

CForwaRD: Personalized CFRD risk assessment looking ahead 1, 2, and 5 years after the most recent OGTT.

Location: Theater A Exhibit Hall

Speaker: – Johns Hopkins University School of Medicine

10:15 AM - 11:45 AM PDT

The role and impact of antifungals in the treatment of allergic bronchopulmonary aspergillosis in cystic fibrosis

Location: Theater A Exhibit Hall

Speaker: – University of Pennsylvania Perelman School of Medicine

10:15 AM - 12:15 PM PDT

W18--Bringing Health Equity into Care

Location: 435

Chair: – Brigham and Women’s Hospital, Division of Global Health Equity

Chair: – University of Pittsburgh

HEACSW/PSYCHCLIN

10:15 AM - 12:15 PM PDT

W18.1- Progression of Cystic Fibrosis Care in Egypt

Location: 435

Speaker: – University of Michigan Health

10:15 AM - 12:15 PM PDT

W18.2- Holding Complexity: Sustaining Equity Efforts in CF Care through Reflection, Accountability, and Adaptation

Location: 435

Speaker: – Boston Children's Hospital

10:15 AM - 12:15 PM PDT

W18.3- Equitable care: MyChart Spanish

Location: 435

Speaker: – Children's Healthcare of Atlanta

10:15 AM - 12:15 PM PDT

W18.4- “But you’re Black and not Skinny”: Photovoice insights on racism and structural inequities among BIPOC individuals with CF

Location: 435

Speaker: – UNC

10:15 AM - 12:15 PM PDT

W18.5- Intersectional lived experiences of LGBTQIA+ people with cystic fibrosis: A qualitative interview study

Location: 435

Speaker: – West Virginia University Department of Pediatrics

10:15 AM - 12:15 PM PDT

W19--Epidemiology & Clinical Impact of Infection in CF

Location: Ballroom 3

Chair: – University of Iowa

Chair: – University of Colorado

IMICLIN

10:15 AM - 12:15 PM PDT

W19.1- Impact of elexacaftor/tezacaftor/ivacaftor (ELX/TEZ/IVA) on healthcare resource utilization (HCRU) over three years in LONGITUDE – a UK CF Registry observational study

Location: Ballroom 3

Speaker: – Vertex Pharmaceuticals

10:15 AM - 12:15 PM PDT

W19.2- Risk factors for pulmonary exacerbation in people with cystic fibrosis taking elexacaftor/tezacaftor/ivacaftor who stop chronic daily therapies

Location: Ballroom 3

Speaker: – Children's Hospital of Philadelphia

10:15 AM - 12:15 PM PDT

W19.3- Epidemiology of Pseudomonas aeruginosa infection before and after the 2013 Infection Prevention and Control Guidelines

Location: Ballroom 3

Speaker: – University of Michigan Medical School

10:15 AM - 12:15 PM PDT

W19.4- The CF Home Sputum-Induction Trial (CF-HomeSpIT) : Primary outcome data for early morning sputum-induction at home compared to same-day sputum-induction in clinic.

Location: Ballroom 3

Speaker: – The Children's Hospital for Wales, Cardiff, UK

10:15 AM - 12:15 PM PDT

W19.5- Evaluating the clinical utility of oropharyngeal swabs from children with cystic fibrosis on elexacaftor/tezacaftor/ivacaftor using shotgun metagenomics

Location: Ballroom 3

Speaker: – University of Iowa

10:15 AM - 12:15 PM PDT

W20--Cutting-edge Clinical Trials: Insights & Updates

Location: Flex A

Chair: – University of North Carolina at Chapel Hill

Chair: – Indiana University

CLIN

10:15 AM - 12:15 PM PDT

W20.1- Comparative clinical outcomes of Trikafta® versus bioequivalent ETI formulations in the management of Cystic Fibrosis in adults: a real world experience

Location: Flex A

Speaker: – HIGA R Rossi

10:15 AM - 12:15 PM PDT

W20.2- A Phase II study (CLAIRAFLY®) evaluating safety, tolerability, pharmacokinetics and pharmacodynamics of the DPP1 (CatC) inhibitor BI 1291583 in cystic fibrosis: Effects of CFTR modulator therapy use

Location: Flex A

Speaker: – Charité - Universitätsmedizin Berlin

10:15 AM - 12:15 PM PDT

W20.3- Safety, tolerability, and pharmacokinetics of novel NBD1 stabilizers SION-719 and SION-451 from two phase 1 first-in-human studies

Location: Flex A

Speaker: – Sionna Therapeutics

10:15 AM - 12:15 PM PDT

W20.4- Nutritional decline and glycemic variability as early clinical indicators in pediatric cystic fibrosis patients undergoing CGM: a retrospective cohort analysis

Location: Flex A

Speaker: – Stanford Medicine Children's Health

10:15 AM - 12:15 PM PDT

W20.5- Artificial intelligence integrating gut microbiome multi-omics to predict clinical outcomes in children with cystic fibrosis

Location: Flex A

Speaker: – The University of New South Wales

10:15 AM - 12:15 PM PDT

W21--Updates in Care

Location: 431-432

Chair: – Manchester Adult Cystic Fibrosis Centre, UK

Chair: – UCLA

PT&RT

10:15 AM - 12:15 PM PDT

W21.1- Tutorial video improves huff cough quality in patients with cystic fibrosis using a novel measure to objectively assess technique.

Location: 431-432

Speaker: – The Children's Hospital of the King's Daughters

10:15 AM - 12:15 PM PDT

W21.2- Oxygen supplementation in pregnancy with cystic fibrosis: A data-driven assessment

Location: 431-432

Speaker: – Nebraska Medicine

10:15 AM - 12:15 PM PDT

W21.3- Optimizing Health: Virtual program to improve health literacy and self-efficacy for children with CF aged 8-12 years. It’s the GOAT!

Location: 431-432

Speaker: – Primary Children's Hospital

10:15 AM - 12:15 PM PDT

W21.4- Balance and Mobility Deficits in Persons with Cystic Fibrosis: Neural Mechanisms and Physical Manifestations

Location: 431-432

Speaker: – Oregon Health & Science University (OHSU)

10:15 AM - 12:15 PM PDT

W21.5- Exploring the Impact of Diaphragmatic Breathing Exercises on Lung Function in Children with Cystic Fibrosis

Location: 431-432

Speaker:

10:15 AM - 12:15 PM PDT

W22--Reprogramming Immune Dysfunction in CF

Location: 436

Chair: – University of Alabama at Birmingham

Chair: – Yale University

APPTTIMI

10:15 AM - 12:15 PM PDT

W22.1- Bioenergetic and metabolic derangements in circulating CF neutrophils are further enhanced by transmigration to the CF airway milieu

Location: 436

Speaker: – Emory University

10:15 AM - 12:15 PM PDT

W22.2- Chronic cystic fibrosis airway disease is driven by MALAT1+ extracellular vesicles via an HDAC11-dependent mechanism.

Location: 436

Speaker: – Emory University

10:15 AM - 12:15 PM PDT

W22.3- LAP it up: The role of LC3 Associated Phagocytosis (LAP) in Cystic Fibrosis (CF)

Location: 436

Speaker: – Emory University

10:15 AM - 12:15 PM PDT

W22.4- Restoration of ezrin via calpain inhibition reinstates immune function in cystic fibrosis alveolar macrophages.

Location: 436

Speaker: – Yale University School of Medicine

10:15 AM - 12:15 PM PDT

W22.5- T cell memory polyamine metabolism and heterogeneity in CF exacerbation outcomes

Location: 436

Speaker: – National Jewish Health

10:15 AM - 12:15 PM PDT

W23--Enhancing Care Improvements for the Changing CF Landscape

Location: 433-434

Chair: – Children's Hospital of Philadelphia

Chair: – University of Virginia

CLIN

10:15 AM - 12:15 PM PDT

W23.1- Implementing a sustainable process to improve short stature identification and endocrine referral in a pediatric cystic fibrosis clinic

Location: 433-434

Speaker: – Johns Hopkins All Children's Hospital

10:15 AM - 12:15 PM PDT

W23.2- Implementing a Preschool Behavioral Health Screener within a Cystic Fibrosis Clinic Flow.

Location: 433-434

Speaker: – The University of Texas at Southwestern

10:15 AM - 12:15 PM PDT

W23.3- Improving access to audiology diagnostic testing in an adult Cystic Fibrosis (CF) program

Location: 433-434

Speaker: – UC San Diego Health

10:15 AM - 12:15 PM PDT

W23.4- Expanded Use of Remote Objective Monitoring During Telehealth Visits for People with CF Experiencing Acute Symptoms: The EUROPA Project

Location: 433-434

Speaker: – Johns Hopkins University School of Medicine

10:15 AM - 12:15 PM PDT

W23.5- Reaching a new milestone: The need to screen for menopause in women with CF

Location: 433-434

Speaker: – National Jewish Health

10:15 AM - 12:15 PM PDT

W24--New Psychosocial Interventions

Location: 423-425

Chair: – University of Kentucky

Chair: – St. Michael's Hospital, Unity Health Toronto

SW/PSYCH

10:15 AM - 12:15 PM PDT

W24.1- Single-item mental health monitoring: Sensitivity and specificity of the Distress Thermometer in cystic fibrosis

Location: 423-425

Speaker: – Michigan Medicine Department of Pediatrics, CS Mott Children's Hospital

10:15 AM - 12:15 PM PDT

W24.2- Development of a General Mental Health Screener (GEMS-CF) and Modulator Side-Effects (GEMS-Mod-SE) Measure: Preliminary Psychometric Properties

Location: 423-425

Speaker: – Joe DiMaggio Cystic Fibrosis Center

10:15 AM - 12:15 PM PDT

W24.3- Pilot study of the PACE-CF Pain Acknowledgement, Coping, and Empowerment intervention for adults

Location: 423-425

Speaker: – University of Kansas Medical Center

10:15 AM - 12:15 PM PDT

W24.4- Stress less, live more: Coping and Learning to Manage Stress (CALM) telehealth sessions help alleviate severe depression and anxiety symptoms in adults with CF

Location: 423-425

Speaker: – National Jewish Health

10:15 AM - 12:15 PM PDT

W24.5- Creating connection for adults with CF: The impact of CF Circles

Location: 423-425

Speaker: – Cystic Fibrosis Foundation

10:15 AM - 12:15 PM PDT

W25--What Does This Button Do? - Innovations in CF Pharmacotherapy

Location: Signature Room

Chair: – The Hospital for Sick Children

Chair: – Child

PHARM

10:15 AM - 12:15 PM PDT

W25.1- National survey of treatment gaps in type 2 inflammation and cystic fibrosis

Location: Signature Room

Speaker: – University of Utah

10:15 AM - 12:15 PM PDT

W25.2- Financial & administrative impacts on people with cystic fibrosis, pharmacists, and pharmacy technicians at CFF-accredited care centers following changes in pharmaceutical limited distribution network

Location: Signature Room

Speaker: – University of California San Diego

10:15 AM - 12:15 PM PDT

W25.3- Impact of pharmacogenomic profiling on medication use in pediatric patients with cystic fibrosis

Location: Signature Room

Speaker: – UNC Health

10:15 AM - 12:15 PM PDT

W25.4- Physiologically based pharmacokinetic of elexacaftor/tezacaftor/ivacaftor in children with cystic fibrosis: extrapolation of the dosing regimen in children under 2 years of age

Location: Signature Room

Speaker: – URP7323, Pharmacologie Et Évaluation Des Thérapeutiques Chez L'enfant Et La Femme Enceinte Université Paris Cité, Paris, France.

10:15 AM - 12:15 PM PDT

W25.5- Modeling a single variable-time measurement of Elexacaftor/Tezacaftor/Ivacaftor in adults

Location: Signature Room

Speaker: – University of North Carolina- Chapel Hill/ National Jewish Health

10:15 AM - 12:15 PM PDT

W26--Best Abstracts in Endocrinology

Location: Ballroom 1

Chair: – UPMC Children's Hospital of Pittsburgh

Chair: – University of Pennsylvania Perelman School of Medicine

CLIN

10:15 AM - 12:15 PM PDT

W26.1- Bone Mineral Density in Young Children with Cystic Fibrosis Pre- and Post-Elexacaftor/Tezacaftor/Ivacaftor – The BEGIN Study

Location: Ballroom 1

Speaker: – Children's Hospital of Philadelphia

10:15 AM - 12:15 PM PDT

W26.2- Baseline lean mass deficits in adolescents and adults with CF persist 24-30m following elexacaftor/tezacaftor/ivacaftor initiation

Location: Ballroom 1

Speaker: – Children's Hospital of Philadelphia

10:15 AM - 12:15 PM PDT

W26.3- Evaluation of testosterone levels in males with Cystic Fibrosis before and after initiation of Elexacaftor/Tezacaftor/Ivacaftor: Data from the PROMISE study

Location: Ballroom 1

Speaker: – UT Southwestern

10:15 AM - 12:15 PM PDT

W26.4- Pregnancy and early parenthood does not have a detrimental impact on CF-health status in women under a dedicated CF Maternal Health Service in the elexacaftor/tezacaftor/ivacaftor era

Location: Ballroom 1

Speaker: – Royal Brompton Hospital

10:15 AM - 12:15 PM PDT

W26.5- Screening for Diabetes and Pre-diabetes in Cystic Fibrosis Using a Non-fasting 50g 1 Hour Oral Glucose Challenge Test

Location: Ballroom 1

Speaker: – University of Colorado, Anschutz Medical Campus

10:15 AM - 12:15 PM PDT

W27--LEAPP in the Best Abstracts in Nursing & Advance Practice Providers

Location: 420-422

Chair: – University of Minnesota

Chair:

Chair: – Stanford University

NRS

10:15 AM - 12:15 PM PDT

W27.1- Increasing respiratory syncytial virus (RSV) vaccination rates in adult cystic fibrosis clinic

Location: 420-422

Speaker: – UC San Diego Health

10:15 AM - 12:15 PM PDT

W27.2- Transitioning to Adult Care: Exploring the Experiences and Challenges of People with Cystic Fibrosis in the Post-HEMT Era

Location: 420-422

Speaker: – University of Cincinnati -

10:15 AM - 12:15 PM PDT

W27.3- Improving the immunization rates in a large paediatric cystic fibrosis clinic

Location: 420-422

Speaker: – QLD HEALTH

10:15 AM - 12:15 PM PDT

W28--Nutritional Breakthroughs: A Workshop on Evidenced-based Nutrition

Location: Ballroom 2

Chair: – WVU Medicine

Chair: – University Health

NTR

10:15 AM - 12:15 PM PDT

W28.1- An evaluation of fecal metabolomics and markers of intestinal integrity in individuals with advanced cystic fibrosis liver disease (aCFLD) and the effect of Elexacaftor-Tezacaftor-Ivacaftor (ETI)

Location: Ballroom 2

Speaker: – Division of Gastroenterology and Hepatology, Department of Pediatrics, University of Washington and Seattle Children's Hospital, Seattle, WA, USA

10:15 AM - 12:15 PM PDT

W28.2- Multivariate classification of gut symptoms in people with CF identifies four phenotypes

Location: Ballroom 2

Speaker: – Imperial College

10:15 AM - 12:15 PM PDT

W28.3- Gut research advancing a mechanistic & personalised understanding of symptoms in CF (GRAMPUS-CF): clinical manifestations

Location: Ballroom 2

Speaker: – Queen's University Belfast

10:15 AM - 12:15 PM PDT

W28.4- Fecal microbiota changes in people with cystic fibrosis after 6 months of elexacaftor/tezacaftor/ivacaftor: Findings from the PROMISE study

Location: Ballroom 2

Speaker: – UCSF Benioff Children's Hospital Oakland

10:15 AM - 12:15 PM PDT

W28.5- G542X small intestine exhibit modest inflammation without structural damage

Location: Ballroom 2

Speaker: – Case Western Reserve University

10:15 AM - 12:15 PM PDT

W29--Don’t STOP Believing: Solutions to Readthrough of PTCs

Location: Terrace Suite

Chair: – FCUL-Faculty of Sciences, University of Lisboa

Chair: – University of Rochester School of Medicine and Dentistry

PTAC/CFTR

10:15 AM - 12:15 PM PDT

W29.1- Genome-Wide KO Screen (GWS) to uncover genes promoting Premature Termination Codon readthrough

Location: Terrace Suite

Speaker: – Cystic Fibrosis Foundation

10:15 AM - 12:15 PM PDT

W29.2- CFTR glutamic acid nonsense mutations are rescued by a newly engineered suppressor transfer RNA in a variant-dependent manner

Location: Terrace Suite

Speaker: – Indiana University

10:15 AM - 12:15 PM PDT

W29.3- Targeted eRF3a degradation amplifies nonsense mutation readthrough in a CF murine model.

Location: Terrace Suite

Speaker: – Case Western Reserve University.

10:15 AM - 12:15 PM PDT

W29.4- Small Molecules as Aminoglycoside Enhancers to promote Readthrough for the Treatment of Cystic Fibrosis

Location: Terrace Suite

Speaker: – Heersink School of Medicine, University of Alabama at Birmingham

10:15 AM - 12:15 PM PDT

W29.5- Discovery of non-aminoglycoside small molecules that enhance eRF3 degrader-induced translational readthrough of CFTR nonsense mutations

Location: Terrace Suite

Speaker:

10:15 AM - 12:15 PM PDT

Lung function decline persists among healthy children with CF taking elexacaftor/tezacaftor/ivacaftor

Location: Theater A Exhibit Hall

Speaker: – Cincinnati Children's Hospital Medical Center

12:15 PM - 1:15 PM PDT

Poster Session: All Odd Numbered Posters

12:15 PM - 2:30 PM PDT

Visit Exhibits and Posters (Refreshments Available)

12:30 PM - 1:20 PM PDT

FSC05--A Conversation with Kecia Nelson

Location: Fireside Chat A Exhibit Hall

Speaker: – MU Children's Hospital

Facilitator: – Hartford Healthcare, Hartford, CT, USA

SW/PSYCH

12:30 PM - 1:20 PM PDT

FSC06--A Conversation with Greg Sawicki

Location: Fireside Chat B Exhibit Hall

Speaker: – Boston Children's Hospital

Facilitator: – CF Foundation

HEAC

12:30 PM - 1:30 PM PDT

Junior Investigators Competition: Top 5 Best Abstract in Clinical Research

Location: 323-325

Chair: – Massachusetts General Hospital/Harvard Medical School

Chair: – Riley Hospital for Children at Indiana University Health

Judge: – University of Pennsylvania

Judge: – Joe DiMaggio Cystic Fibrosis Center

Judge: – Medical College of Wisconsin / Children's Wisconsin

Judge:

Judge: – Cystic Fibrosis Foundation

12:30 PM - 1:30 PM PDT

Junior Investigators Competition: Top 5 Best Abstract in Basic Science

Location: 347-348

Chair: – Emory University School of Medicine

Chair: – Columbia University Irving Medical Center

Judge:

Judge: – University of Washington and VA Puget Sound Health Care System

Judge: – University of Michigan

Judge: – University of Washington

Judge: – Yale University

Judge: – University of North Carolina

1:15 PM - 2:15 PM PDT

Poster Session: All Even Numbered Posters

1:30 PM - 2:20 PM PDT

FSC07--A Conversation with Katie McDonald

Location: Fireside Chat A Exhibit Hall

Speaker: – Primary Children's Hospital

Facilitator: – Primary Children's Cystic Fibrosis Center

NTR

1:30 PM - 2:20 PM PDT

FSC08--A Conversation with Janet Garbarz

Location: Fireside Chat B Exhibit Hall

Speaker: – Cook Children's Medical Center

Facilitator: – Rush University Medical Center

NRS

2:30 PM - 4:00 PM PDT

Comparing mucociliary clearance patterns between modulator treated-cystic fibrosis, healthy controls, and non-cystic fibrosis bronchiectasis

Location: Theater A Exhibit Hall

Speaker: – University of North Carolina at Chapel Hill

2:30 PM - 4:00 PM PDT

Using longitudinal HbA1c to predict Cystic Fibrosis Related Diabetes

Location: Theater A Exhibit Hall

Speaker: – University of Colorado

2:30 PM - 4:00 PM PDT

Changes in sweat chloride concentrations following CFTR modulator treatment and association with antibiotic usage in adolescents and adults with cystic fibrosis

Location: Theater A Exhibit Hall

Speaker: – Department of Pulmonary Medicine, Division of Cystic Fibrosis, University Medicine Essen -Ruhrlandklinik, University of Duisburg-Essen, Essen, Germany.

2:30 PM - 4:00 PM PDT

Sweat sodium: chloride ratio differs in people with CF by CFTR modulator treatment status

Location: Theater A Exhibit Hall

Speaker: – University of Colorado School of Medicine

2:30 PM - 4:00 PM PDT

Evaluation of the variability of exhaled breath profiles for the detection of Pseudomonas aeruginosa infections in cystic fibrosis: A longitudinal study

Location: Theater A Exhibit Hall

Speaker: – University of British Columbia

2:30 PM - 4:00 PM PDT

Volatile biomarkers can differentiate methicillin-resistant and small-colony variant S. aureus subtypes in-vitro

Location: Theater A Exhibit Hall

Speaker: – Arizona State University

2:30 PM - 4:00 PM PDT

Continuous glucose monitoring in young children with cystic fibrosis: a BEGIN sub-study

Location: Theater A Exhibit Hall

Speaker: – University of Iowa

2:30 PM - 4:00 PM PDT

Is epigenetic age a marker of CF severity and drug response?

Location: Theater A Exhibit Hall

Speaker: – The Hospital for Sick Children

2:30 PM - 4:00 PM PDT

Maximizing benefits with early CFTR modulator treatment: Lower sweat chloride is associated with improved clinical outcomes in children aged 6 to 11 years

Location: Theater A Exhibit Hall

Speaker: – Department of Pediatrics, Division of Pulmonology, Asthma, Cystic Fibrosis, and Sleep, Emory University School of Medicine

2:30 PM - 4:00 PM PDT

Parameter D: A novel biomarker to detect small airway disease through spirometry in cystic fibrosis

Location: Theater A Exhibit Hall

Speaker: – UAB

2:30 PM - 4:00 PM PDT

TPS05--Biomarkers of Disease Severity & Outcome Measures of Therapeutic Efficacy

Location: Theater A Exhibit Hall

Chair: – Riley Hospital for Children at Indiana University Health

Chair: – Arkansas Children's Hospital/Arkansas Children's Research Institute

APPTTCLIN

2:30 PM - 4:30 PM PDT

S13--CF Endocrinology Across the Lifespan

Location: 431-432

Chair: – University of Texas Health San Antonio

Chair: – University of Florida - Gainesville

CLIN

2:30 PM - 4:30 PM PDT

S13.1- Updates on Growth and Puberty

Location: 431-432

Speaker: – Yale Medical Center

2:30 PM - 4:30 PM PDT

S13.2- CF-Bone Disease: From Childhood to Adulthood

Location: 431-432

Speaker: – Johns Hopkins University School of Medicine

2:30 PM - 4:30 PM PDT

S13.3- Male Endocrine and Reproductive Health

Location: 431-432

Speaker: – Rutgers Urology

2:30 PM - 4:30 PM PDT

S13.4- Modern CFRD: Devices, Expanding Therapies, and Addressing Obesity

Location: 431-432

Speaker: – University of Florida - Gainesville

2:30 PM - 4:30 PM PDT

S14--Molecular Basis of Persistent Infection

Location: Ballroom 1

Chair: – University of Alabama at Birmingham

Chair: – University of Maryland - Baltimore

IMI

2:30 PM - 4:30 PM PDT

S14.1- Mechanisms of Staphylococcus Aureus Pathoadaptation in CF

Location: Ballroom 1

Speaker: – University of Münster

2:30 PM - 4:30 PM PDT

S14.2- Pseudomonas Aeruginosa Persistence in the CF Airways

Location: Ballroom 1

Speaker: – University of Washington

2:30 PM - 4:30 PM PDT

S14.3- Polymicrobial Mechanisms of Bacterial Persistence in CF

Location: Ballroom 1

Speaker: – Indiana University Bloomington

2:30 PM - 4:30 PM PDT

S14.4- Anaerobes and Emerging CF Pathogens

Location: Ballroom 1

Speaker: – Children's Hospital of Philadelphia

2:30 PM - 4:30 PM PDT

S15--From Crisis to Care: Tackling the Lung Transplant Journey

Location: 423-425

Chair: – Northwell Health

Chair: – University of California, Los Angeles (UCLA)

SW/PSYCH

2:30 PM - 4:30 PM PDT

S15.1- Patient / Caregiver VIDEO

Location: 423-425

Community Speaker: – Private

Community Speaker: – Queens University of Charlotte

2:30 PM - 4:30 PM PDT

S15.2- Psychotherapy and BOLT: Insights from a Therapist and CF Family Member

Location: 423-425

Speaker: – Inova Fairfax

2:30 PM - 4:30 PM PDT

S15.3- Improved Alcohol Use Screening & Other Pearls of Wisdom from a CF and LT MD

Location: 423-425

Speaker: – UCLA

2:30 PM - 4:30 PM PDT

S15.4- One Pediatric Patient Perspective: A CF MD Perspective of the challenges of Pre/Post Transplant Care

Location: 423-425

Speaker: – West Virginia University

2:30 PM - 4:30 PM PDT

S16--The Promise of Nucleic Acid-Based Therapies in CF: Progress & Prospects

Location: 420-422

Chair: – Washington University in St. Louis

Chair: – Division of Pulmonary Medicine, Cincinnati Children’s Hospital, Cincinnati, Ohio, USA

PTAC/CFTR

2:30 PM - 4:30 PM PDT

S16.1- Progress on antisense oligonucleotide therapies in cystic fibrosis

Location: 420-422

Speaker: – Hebrew University

2:30 PM - 4:30 PM PDT

S16.2- Lentiviral gene therapy – the journey into the clinic

Location: 420-422

Speaker: – National Heart and Lung Institute, Imperial College London

2:30 PM - 4:30 PM PDT

S16.3- Editing the CFTR gene

Location: 420-422

Speaker: – Division of Pulmonary Medicine, Cincinnati Children’s Hospital, Cincinnati, Ohio, USA

2:30 PM - 4:30 PM PDT

S16.4- Real-world challenges & perspectives

Location: 420-422

Speaker: – Washington University in St. Louis

2:30 PM - 4:30 PM PDT

S17--Early Diagnosis vs. Late Diagnosis: Compare & Contrast

Location: Signature Room

Chair: – NYU

Chair: – UW Health

NRS

2:30 PM - 4:30 PM PDT

S17.1- Diagnosis Mixed Bag: Newborn to Adult and Everything in Between

Location: Signature Room

Speaker: – Dartmouth Hitchcock

2:30 PM - 4:30 PM PDT

S17.2- Teenage CF Diagnosis: Challenges and Successes

Location: Signature Room

Speaker: – University of Utah

2:30 PM - 4:30 PM PDT

S17.3- Navigating a New Diagnosis- The First Year of Life

Location: Signature Room

Speaker: – University of Utah

2:30 PM - 4:30 PM PDT

S17.4- A Little Late, but Look at Me Now

Location: Signature Room

Speaker: – Indiana University Adult CF Center

Community Speaker:

2:30 PM - 4:30 PM PDT

S18--Individualizing Nutrition Care: A Health Behavior Perspective

Location: Flex A

Chair: – UT Health San Antonio

Chair: – Baylor Scott and white

NTR

2:30 PM - 4:30 PM PDT

S18.1- Pros and Cons of GLP-1 agonists

Location: Flex A

Speaker:

2:30 PM - 4:30 PM PDT

S18.2- Individual Experience of Body Image Changes with Modulators

Location: Flex A

Speaker: – Patient with CF

2:30 PM - 4:30 PM PDT

S18.3- Individual Experience of Body Image Changes with Modulators

Location: Flex A

Speaker:

2:30 PM - 4:30 PM PDT

S18.4- Weight Inclusive Approach to Counseling Patients and Caregivers

Location: Flex A

Speaker: – Cincinnati Children's Hospital Medical Center, Divisions of Behavioral Medicine and Clinical Psychology & Pulmonary Medicine

2:30 PM - 4:30 PM PDT

S19--Don’t Sweat It: Navigating the Relationship Between Sweat Chloride & Clinical Outcomes in CF

Location: 435

Chair: – University of Washington

Chair: – Children's Hospital Colorado, Univ. of Colorado Anschutz Med. Campus

CLIN

2:30 PM - 4:30 PM PDT

S19.1- Is Sweating Enough? Biomarkers of CFTR Function

Location: 435

Speaker: – Charité - Universitätsmedizin Berlin

2:30 PM - 4:30 PM PDT

S19.2- Relationship Between Genotype, CFTR Activity, and Clinical Phenotype

Location: 435

Speaker: – Johns Hopkins University

2:30 PM - 4:30 PM PDT

S19.3- Sweat Signals: Use of Sweat Chloride in Clinical Trials of CFTR Modulators

Location: 435

Speaker: – Department of Pediatrics, Division of Pulmonology, Asthma, Cystic Fibrosis, and Sleep, Emory University School of Medicine

2:30 PM - 4:30 PM PDT

S19.4- Promise and Pitfalls in Sweat Chloride Use for Clinical Monitoring and Therapeutics Development

Location: 435

Speaker: – Children's Hospital Colorado, Univ. of Colorado Anschutz Med. Campus

2:30 PM - 4:30 PM PDT

S20--Modulator Effects on Different Organ Systems

Location: Terrace Suite

Chair: – Boston Children's Hospital

Chair: – Advocate Children's Hospital

EPPPTAC/CFTR

2:30 PM - 4:30 PM PDT

S20.1- Title: TBD

Location: Terrace Suite

Speaker: – Hasbro Children's Hospital

2:30 PM - 4:30 PM PDT

S20.2- Title: TBD

Location: Terrace Suite

Speaker: – Division of Gastroenterology and Hepatology, Department of Pediatrics, University of Washington and Seattle Children's Hospital, Seattle, WA, USA

2:30 PM - 4:30 PM PDT

S20.3- Title: TBD

Location: Terrace Suite

Speaker: – Emory University/Childrens Atlanta

2:30 PM - 4:30 PM PDT

S20.4- Title: TBD

Location: Terrace Suite

Speaker: – Massachusetts General Hospital/Harvard Medical School

2:30 PM - 4:30 PM PDT

S21--For Your Consideration: A Debate on De-escalating Therapies?

Location: 427-429

Chair: – Provincial Health Services Authority

Chair: – Wellstar MCG Health Children's Hospital of Georgia

PT&RT

2:30 PM - 4:30 PM PDT

Pro Argument: De-Escalation of Airway Clearance

Location: 427-429

Speaker: – Private Practice

2:30 PM - 4:30 PM PDT

S21.2- Con Argument: De-Escalation of Airway Clearance

Location: 427-429

Speaker: – Monash University

2:30 PM - 4:30 PM PDT

S21.3- Pro Argument: De-Escalation of Mucolytics

Location: 427-429

Speaker: – UH Cleveland Medical Center / Rainbow Babies and Children's

2:30 PM - 4:30 PM PDT

S21.4- Con Argument: De-Escalation of Mucolytics

Location: 427-429

Speaker: – University of North Carolina at Chapel Hill

2:30 PM - 4:30 PM PDT

S21.5- Pro Argument: De-Escalation of Anti-Pseudomonals

Location: 427-429

Speaker: – Wellstar MCG- Children's Hospital of Georgia

2:30 PM - 4:30 PM PDT

S21.6- Con Argument: De-Escalation of Anti-Pseudomonals

Location: 427-429

Speaker: – Riley Hospital for Children at Indiana University Health

2:30 PM - 4:30 PM PDT

S22--Cell Biology Meets Gene Therapy: Challenges of Restoring CFTR Expression in the Lung

Location: Ballroom 2

Chair: – University of Toronto & The Hospital for Sick Children

Chair: – University of Saskatchewan

APPTTPTAC/CFTR

2:30 PM - 4:30 PM PDT

S22.1- Healing the Airway: Human Pluripotent Stem Cell-based Airway Regeneration

Location: Ballroom 2

Speaker:

2:30 PM - 4:30 PM PDT

S22.2- iPSC-Based Approaches to Uncover Ionocyte Function and Therapeutic Potential in CF

Location: Ballroom 2

Speaker: – Boston Children's Hospital

2:30 PM - 4:30 PM PDT

S22.3- Hitting the Target: Challenges and Progress in Delivery to Airway Epithelial Cells

Location: Ballroom 2

Speaker: – University of Iowa

2:30 PM - 4:30 PM PDT

S22.4- Design and Development of Lipid Nanoparticles for Durable CFTR Gene Correction in Lung Stem Cells

Location: Ballroom 2

Speaker:

2:30 PM - 4:30 PM PDT

S23--Year(s) in Review

Location: 433-434

Chair: – Rainbow Babies and Children's Hospital

Chair: – University of Washington

CLIN

2:30 PM - 4:30 PM PDT

S23.1- Quality Improvement and the CF Learning Network (CFLN)

Location: 433-434

Speaker: – Seattle Children's Hospital/UW

2:30 PM - 4:30 PM PDT

S23.2- Lung Transplant and the CF Lung Transplant Consortium (CFLTC)

Location: 433-434

Speaker: – University of Pittsburgh

2:30 PM - 4:30 PM PDT

S23.3- Adherence and the Success with Therapies Research Consortium (STRC)

Location: 433-434

Speaker: – Johns Hopkins University School of Medicine

2:30 PM - 4:30 PM PDT

S23.4- Updates in Pain and Review of Recent Guidelines

Location: 433-434

Community Speaker: – Cystic Fibrosis Foundation

Speaker: – Emory University

Speaker: – UNC Chapel Hill

2:30 PM - 4:30 PM PDT

S24--Beyond Boundaries: Protecting & Supporting Optimal Care for all people with CF

Location: Ballroom 3

Chair: – University of Virginia

Chair: – Boston Children's Hospital

Chair: – University of Alabama at Birmingham

HEACSW/PSYCHNRS

2:30 PM - 4:30 PM PDT

S24.1- Health needs and perspectives of LGBTQIA+ People with CF

Location: Ballroom 3

Speaker: – West Virginia University School of Medicine

2:30 PM - 4:30 PM PDT

S24.2- Immigrant health "Know your rights"

Location: Ballroom 3

Speaker: – Seattle Children's Hospital

2:30 PM - 4:30 PM PDT

S24.3- Health Care Cost and Access in the Current Era

Location: Ballroom 3

Speaker: – Cystic Fibrosis Foundation

2:30 PM - 4:30 PM PDT

S24.4- Men's Reproductive Health

Location: Ballroom 3

Speaker: – Rutgers Urology

2:30 PM - 4:30 PM PDT

S24.5- Panel discussion

Location: Ballroom 3

Speaker: – University of Nevada, Las Vegas - School of Nursing

2:30 PM - 4:30 PM PDT

S25--The New L is Liver

Location: 436

Chair: – Boston Children's Health Physicians

Chair: – Yale University

CLIN

2:30 PM - 4:30 PM PDT

S25.1- Liver Injury in CF Patients

Location: 436

Speaker: – University of Colorado SOM and Children's Hospital Colorado

2:30 PM - 4:30 PM PDT

S25.2- Liver Nutrition in CF Patients

Location: 436

Speaker: – Kidz Medical/Joe Di Maggio Children's Hospital

2:30 PM - 4:30 PM PDT

S25.3- Liver Imaging in pwCF

Location: 436

Speaker: – Nationwide Children's Hospital/The Ohio State University

2:30 PM - 4:30 PM PDT

S25.4- Liver fibrosis markers in CF

Location: 436

Speaker: – Baylor College of Medicine

5:00 PM - 6:15 PM PDT

PL2--A Breath of Fresh Age: Redefining Growing Older with CF

Location: Flex C

Speaker: – Brigham and Women's Hospital and Boston Children's Hospital

Speaker: – Johns Hopkins Hospital

6:30 PM - 7:30 PM PDT

Black Professional in CF Affinity Group

Location: Garden Lounge

6:30 PM - 7:30 PM PDT

LGBTQIA+ Professionals in CF Affinity Group

Location: 439

6:30 PM - 7:30 PM PDT

Hispanic Professionals in CF Affinity Group

Location: Paramount Lounge

7:00 AM - 2:30 PM PDT

Registration Open

Location: Summit Lobby

7:45 AM - 9:45 AM PDT

W30--Gene Editing: Delivery of Gene Editors

Location: Signature Room

Chair: – Johns Hopkins University

Chair: – Nationwide Children's Hospital

PTAC/CFTR

7:45 AM - 9:45 AM PDT

W30.1- Polymeric nanoparticle-mediated adenine base editing targets key airway epithelial cell types for functional restoration of a common CFTR splice variant

Location: Signature Room

Speaker: – Johns Hopkins University School of Medicine

7:45 AM - 9:45 AM PDT

W30.2- A murine Cystic Fibrosis reporter system to assess delivery and duration of gene editing and cell transplantation therapeutics

Location: Signature Room

Speaker: – Case Western Reserve University

7:45 AM - 9:45 AM PDT

W30.3- Antibody/peptide-nanoparticle conjugates for specific cell-type targeting of genetic therapies

Location: Signature Room

Speaker: – University of Michigan

7:45 AM - 9:45 AM PDT

W30.4- Optimizing Prime Editing for Precise Correction of the CFTR G542X Mutation via LNP-Mediated Delivery

Location: Signature Room

Speaker: – University of Toronto

7:45 AM - 9:45 AM PDT

W30.5- Ionizable lipid nanoparticles for gene editing of the fetal lung

Location: Signature Room

Speaker: – University of Pennsylvania and Children's Hospital of Philadelphia

7:45 AM - 9:45 AM PDT

W31--Microbial Ecology & Polymicrobial Interactions of CF Airway Infection

Location: Terrace Suite

Chair: – University of Colorado School of Medicine

Chair: – University of Sherbrooke

IMI

7:45 AM - 9:45 AM PDT

W31.1- Experimentally Evolving a Staphylococcus aureus Cystic Fibrosis Isolate to Resist its Co-isolated Pseudomonas aeruginosa

Location: Terrace Suite

Speaker: – Emory University

7:45 AM - 9:45 AM PDT

W31.2- Pseudomonas aeruginosa rapidly kills non-tuberculous mycobacteria in dual-species biofilms in vitro

Location: Terrace Suite

Speaker: – Radboudumc

7:45 AM - 9:45 AM PDT

W31.3- Alginate scavenging by Achromobacter xylosoxidans mediates competitive interactions with mucoid Pseudomonas aeruginosa during polymicrobial infection

Location: Terrace Suite

Speaker: – University of Alabama at Birmingham

7:45 AM - 9:45 AM PDT

W31.4- Pseudomonas aeruginosa induced GM-CSF production by airway epithelial cells could help protect against Mycobacterium abscessus

Location: Terrace Suite

Speaker: – National Jewish Health

7:45 AM - 9:45 AM PDT

W31.5- Highly effective CFTR modulator therapy (HEMT) alters Staphylococcus and Streptococcus microbiome and phage populations despite Pseudomonas persistence

Location: Terrace Suite

Speaker: – Cedars-Sinai Medical Center

7:45 AM - 9:45 AM PDT

DG23--Living Audit Ready

Location: 345-346

Chair: – Baylor College of Medicine

Chair: – UAB

Speaker: – University of Pennsylvania

Speaker: – Providence Sacred Heart Medical Center and Children's Hospital

Speaker:

CLIN

7:45 AM - 9:45 AM PDT

DG24--Off the Beaten Path: Non-Traditional Approaches to Optimizing Pharmacy Care

Location: 343-344

Chair: – The University of Kansas Health System

Chair: – Ascension Adult CF Center of Central Texas

Speaker: – Helen DeVos Children's Hospital Cystic Fibrosis Care Center

Speaker: – UC Davis Health

Speaker: – University of Missouri

Speaker: – University Health

PHARM

7:45 AM - 9:45 AM PDT

DG25--Hot Topics

Location: 347-348

Chair: – University of Cincinnati -

Chair: – Akron Children's Hospital

Speaker: – NYU

Speaker: – University of Cambridge

Speaker: – University of Vermont Medical Center

Speaker: – University of Minnesota - Pediatric CF Center

Speaker: – University of Utah Health

NRS

7:45 AM - 9:45 AM PDT

DG26--Nutrition in the Life Course Perspective: Women & Health

Location: 320-322

Chair: – Dept of Clinical Nutrition, Boston Children's Hospital

Chair: – University of Minnesota Adult Cystic Fibrosis Center

Speaker: – Indiana University Health

Speaker: – Johns Hopkins University School of Medicine

Speaker: – University of Utah Adult CF Team

Speaker: – Boston Children's Hospital

Speaker: – Dept of Clinical Nutrition, Boston Children's Hospital

NTR

7:45 AM - 9:45 AM PDT

DG27--On the Road Again; Transitions Through the Lifespan of the CF Patient

Location: 331-332

Chair: – Yale New Haven Hospital

Chair: – National Jewish Health-Adult Cystic Fibrosis Clinic

Speaker: – Primary Children's Hospital

Speaker: – Columbia University Irving Medical Center - Adult CF Clinic

PT&RT

7:45 AM - 9:45 AM PDT

Special Session--Strategies to Navigate an Academic Career in CF

Location: 420-422

Chair: – The University of North Carolina at Chapel Hill

Chair: – Vanderbilt University Medical Center

Chair: – University of North Carolina at Chapel Hill

CLINHEAC

8:00 AM - 9:15 AM PDT

CC01--From the Editors' Desks: Best of CF Publications

Location: 335-336

Chair: – Medical University of South Carolina

Chair: – University of Washington School of Medicine

CLIN

8:00 AM - 9:15 AM PDT

CC01.1- Title TBD

Location: 335-336

8:00 AM - 9:15 AM PDT

CC01.2- Title TBD

Location: 335-336

8:00 AM - 9:15 AM PDT

CC01.3- Title TBD

Location: 335-336

8:00 AM - 9:15 AM PDT

CC01.4- Title TBD

Location: 335-336

8:00 AM - 9:15 AM PDT

CC02--Navigating Fear & Stress Through Medical Procedures

Location: 340-342

Chair: – University of Kentucky

Chair: – Children's National Hospital, 111 Michigan Avenue, NW Washington, DC 20010

SW/PSYCH

8:00 AM - 9:15 AM PDT

CC02.1- Title TBD

Location: 340-342

Speaker: – University of California San Francisco

8:00 AM - 9:15 AM PDT

CC02.2- Title TBD

Location: 340-342

Speaker: – University of Kentucky

8:00 AM - 9:15 AM PDT

CC02.3- Title TBD

Location: 340-342

Speaker: – Nemours Children's Health

8:00 AM - 9:15 AM PDT

CC02.4- Title TBD

Location: 340-342

Speaker: – National Jewish Health

8:00 AM - 9:15 AM PDT

CC03--Complex Nutrition/GI Cases: Navigating the Extremes and Everything in Between

Location: 327-329

Chair: – Danat Al Emarat Hospital

Chair: – Baylor College of Medicine

NTRCLIN

8:00 AM - 9:15 AM PDT

CC03.1- Identifying secondary sclerosing cholangitis in the cystic fibrosis patient

Location: 327-329

Speaker: – Rutgers Robert Wood Johnson Medical School

8:00 AM - 9:15 AM PDT

CC03.2- What happens to the aging CF pancreas

Location: 327-329

Speaker: – Froedtert Hospital and the Medical College of Wisconsin

8:00 AM - 9:15 AM PDT

CC03.3- Recurrent Distal Intestinal Obstruction Syndrome in CF-Related Diabetes treated with a GLP-1 Agonist.

Location: 327-329

Speaker: – Wright State University Boonshoft School of Medicine

8:00 AM - 9:15 AM PDT

CC03.4- Feeding challenges in an infant with cystic fibrosis and FPIES.

Location: 327-329

Speaker: – Northwell Lenox Hill

8:00 AM - 9:15 AM PDT

CC04--The Wild World of CF Genetics

Location: 333-334

Chair: – Lenox Hill Hospital/Northwell Health

Chair: – Johns Hopkins All Children's Hospital

CLIN

8:00 AM - 9:15 AM PDT

CC04.1- Prenatal Testing for CF: Helpful or Confusing?

Location: 333-334

Speaker: – Children’s Hospital of Michigan

8:00 AM - 9:15 AM PDT

CC04.2- Cascade Diagnoses Within a Family

Location: 333-334

Speaker: – Primary Childrens Medical Center

8:00 AM - 9:15 AM PDT

CC04.3- 34 yo CFTR carrier with mixed clinical picture of testicular failure and unilateral obstructive azoospermia in setting of bilateral palpable vas deferens.

Location: 333-334

Speaker: – University of Texas at Austin Dell Medical School

8:00 AM - 9:15 AM PDT

CC04.4- Aquagenic Keratoderma as a Diagnostic Clue to CF in a Patient with Only One Known CTFR Mutation

Location: 333-334

Speaker: – University of Massachusetts Medical Center

8:00 AM - 9:15 AM PDT

CC05--Troubleshooting Complex Cases Dealing with Social Determinants of Health & Complex Insurance Issues

Location: 447-448

Chair: – University of Utah

Chair: – The University of Kansas Health System

NRSHEACSW/PSYCH

8:00 AM - 9:15 AM PDT

CC05.1- There's No Place Like Home: A Case Study Exploring the Role of SDOH in an Individual with CF

Location: 447-448

Speaker: – Michigan Medicine

8:00 AM - 9:15 AM PDT

CC05.2- Complex Insurance Cases - Maintaining Access to Care

Location: 447-448

Speaker: – The University of Kansas Health System

8:00 AM - 9:15 AM PDT

CC05.3- Late Blooming CF: When Social Complexities Meet New Complex Chronic Disease Diagnosis

Location: 447-448

Speaker: – UCLA

8:00 AM - 9:15 AM PDT

CC05.4- Improving Care for a Pediatric Patient with Complex SDOH by Collaborating with a PCP

Location: 447-448

Speaker: – University of Utah

8:00 AM - 9:15 AM PDT

CC05.5- Patient 1: Latina Patient with a Complex Social History & Insurance Barriers that Affected Care & Outcomes

Location: 447-448

Speaker: – Emory Adult CF Clinic

8:00 AM - 9:15 AM PDT

CC06--It's Complicated: A Review of Complex Patients Therapies & Outcomes

Location: 323-325

Chair: – Children's Healthcare of Atlanta

Chair: – Western Michigan University Homer Stryker M.D. School of Medicine

PT&RT

8:00 AM - 9:15 AM PDT

CC06.1- Back to the Basics

Location: 323-325

Speaker: – University of California, San Francisco

8:00 AM - 9:15 AM PDT

CC06.2- A six year look at recurrent exacerbations despite aggressive airway clearance: Where to go from here?

Location: 323-325

Speaker: – Michigan Medicine - Adult Cystic Fibrosis Clinic

8:00 AM - 9:15 AM PDT

CC06.3- Assessing balance and vestibular issues in adults with CF

Location: 323-325

Speaker: – UCLA

8:00 AM - 9:15 AM PDT

CC06.4- Resistance Training Effect on Bone Density in an Adult Setting

Location: 323-325

Speaker: – Adult Cystic Fibrosis Center of Central Texas

8:00 AM - 11:00 AM PDT

Exhibit & Poster Hall Open

8:15 AM - 9:45 AM PDT

TPS06--Nourishing Horizons: Innovations in GI, Endocrine, & Nutrition in CF

Location: Theater A Exhibit Hall

Chair: – Rutgers Robert Wood Johnson Medical School

Chair: – Massachusetts General Hospital

NTRCLIN

8:15 AM - 9:45 AM PDT

ANG003, a non-porcine pancreatic enzyme replacement therapy, provides significantly higher enzymatic activity than porcine products over the range of gastrointestinal pHs and USP monograph pH 9

Location: Theater A Exhibit Hall

Speaker: – Anagram Therapeutics

8:15 AM - 9:45 AM PDT

Comparison of Continuous Glucose Monitoring to the Oral Glucose Tolerance Test as a screen for Cystic fibrosis-related diabetes.

Location: Theater A Exhibit Hall

Speaker: – Froedtert Health

8:15 AM - 9:45 AM PDT

Efficacy and safety of GLP-1 agonist therapy in overweight and obese subjects with cystic fibrosis-related diabetes: A pilot study

Location: Theater A Exhibit Hall

Speaker: – University of Minnesota

8:15 AM - 9:45 AM PDT

Using RELiZORB® (Immbolized Lipase Cartridge) for Surgical Cystic Fibrosis Infants in the Neonatal Intensive Care Unit.

Location: Theater A Exhibit Hall

Speaker: – CCHMC

8:15 AM - 9:45 AM PDT

Dietary Linoleic Acid is Associated with Increased Adiposity in Adults with Cystic Fibrosis Not Taking CFTR Modulators.

Location: Theater A Exhibit Hall

Speaker: – Emory University

8:15 AM - 9:45 AM PDT

Probiotics and the EARly Life effects on intestinal bacteria and inflammation in children with Cystic Fibrosis (PEARL-CF) Study.

Location: Theater A Exhibit Hall

Speaker: – UNSW Sydney; Sydney Children's Hospital Randwick, NSW, Australia

8:15 AM - 9:45 AM PDT

Fibrosis Biomarkers in Pediatric Cystic Fibrosis Liver Disease: A Useful Tool for Screening

Location: Theater A Exhibit Hall

Speaker: – UMKC School of Medicine, University of Texas Southwestern/Children’s Health

8:15 AM - 9:45 AM PDT

Factors that Increase Likelihood of 30-Day Hospital Readmissions in Patients with Cystic Fibrosis: A National Readmissions Database Study.

Location: Theater A Exhibit Hall

Speaker:

8:15 AM - 9:45 AM PDT

Burden of digestive system complications in the cystic fibrosis community

Location: Theater A Exhibit Hall

Speaker: – Cystic Fibrosis Foundation

8:15 AM - 9:45 AM PDT

Dynamic time warping analysis of continuous glucose monitoring reveals significant dysglycemia that is underestimated by oral glucose tolerance test classification

Location: Theater A Exhibit Hall

Speaker: – Duke University

9:00 AM - 11:00 AM PDT

Coffee Break in the Exhibit Hall

10:15 AM - 12:15 PM PDT

S26--Charting the Course: Tackling the Challenges of Healthcare Accessibility

Location: 431-432

Chair: – University of Missouri

Chair: – Geisel School of Medicine

HEACSW/PSYCHPHARM

10:15 AM - 12:15 PM PDT

S26.1- Navigating the Complexities of Healthcare Insurance for Cystic Fibrosis

Location: 431-432

Speaker: – CF Foundation

10:15 AM - 12:15 PM PDT

S26.2- Understanding the Process: How PBMs Affect Your Medication Accessibility

Location: 431-432

Speaker:

10:15 AM - 12:15 PM PDT

S26.3- The Future of Healthcare Insurance: Trends and Updates

Location: 431-432

Speaker: – Cystic Fibrosis Foundation

10:15 AM - 12:15 PM PDT

S26.4- Transforming Healthcare: The Role of SDoH Assessment

Location: 431-432

Speaker: – University of Missouri

10:15 AM - 12:15 PM PDT

S27--Phage is the Rage: Demystifying Phage Therapy

Location: Ballroom 3

Chair: – The Hospital for Sick Children

Chair: – Yale University

IMI

10:15 AM - 12:15 PM PDT

S27.1- Current status of phage therapy clinical trials

Location: Ballroom 3

Speaker: – National Jewish Health

10:15 AM - 12:15 PM PDT

S27.2- Phage therapy in pediatric pwCF

Location: Ballroom 3

Speaker: – Children’s National Hospital

10:15 AM - 12:15 PM PDT

S27.3- NTM phages

Location: Ballroom 3

Speaker: – Georgia State University

10:15 AM - 12:15 PM PDT

S27.4- Single-sequential phage therapy for Pseudomonas in pwCF

Location: Ballroom 3

Speaker: – Yale University

10:15 AM - 12:15 PM PDT

S28--Sexual & Reproductive Health in CF

Location: Ballroom 2

Chair: – Children's Mercy Kansas City

Chair: – UC San Diego Health

NRS

10:15 AM - 12:15 PM PDT

S28.1- An Overview of the CFF Sexual and Reproductive Health Position Paper

Location: Ballroom 2

Speaker: – Children's Mercy Kansas City

10:15 AM - 12:15 PM PDT

S28.2- Reproductive Health in Males in CF: Options for Family Building and Men’s Health

Location: Ballroom 2

Speaker: – Rutgers Urology

10:15 AM - 12:15 PM PDT

S28.3- Just the Facts: Contraception in the era of CFTR modulators

Location: Ballroom 2

Speaker: – UVA Health

10:15 AM - 12:15 PM PDT

S28.4- Having the hard conversations: Normalizing sexual and reproductive health discussion in a pediatric CF center

Location: Ballroom 2

Speaker: – CHOC Children's

Speaker: – CHOC

10:15 AM - 12:15 PM PDT

S29--Diagnostic Challenges Across the Lifespan

Location: Terrace Suite

Chair: – UH Cleveland Medical Center / Rainbow Babies and Children's

Chair: – University of Washington / Seattle Children's Hospital

CLIN

10:15 AM - 12:15 PM PDT

S29.1- CFTR-Related Disorders

Location: Terrace Suite

Speaker: – Royal Brompton Hospital

10:15 AM - 12:15 PM PDT

S29.2- Title TBD

Location: Terrace Suite

10:15 AM - 12:15 PM PDT

S29.3- Title TBD

Location: Terrace Suite

10:15 AM - 12:15 PM PDT

S29.4- Title TBD

Location: Terrace Suite

10:15 AM - 12:15 PM PDT

S30.1- Mechanism of Action of X316761, A Highly Efficacious Potentiator, Studied Using Structural Biology & Electrophysiology

Location: 423-425

Speaker: – University of Missouri

10:15 AM - 12:15 PM PDT

S30.2- Stabilizing Nanobody Reveal a Novel Active State of CFTR: Implications for Correction of F508del-CFTR

Location: 423-425

Speaker: – Universite Libre de Bruxelles

10:15 AM - 12:15 PM PDT

S30.3- Coupled Protein & Lipid Phase Separation Modulates CFTR Clustering on Membranes

Location: 423-425

Speaker:

10:15 AM - 12:15 PM PDT

S30.4- Combined In Silico/In Vitro Screens Enable Identification of Hits with Both Potentiator & Corrector Action

Location: 423-425

Speaker: – University College London (UCL)

10:15 AM - 12:15 PM PDT

S30--Mechanistic Insight Into CFTR Function & Modulation

Location: 423-425

Chair: – School of Physiology, Pharmacology and Neuroscience, University of Bristol

Chair: – The Hospital for Sick Children

PTAC/CFTR

10:15 AM - 12:15 PM PDT

S31--It's New & Improved! Innovations in RT/PT

Location: 436

Chair: – Inova Fairfax Hospital

Chair: – West of Scotland Adult CF Unit

PT&RT

10:15 AM - 12:15 PM PDT

S31.1- Quality Over Quantity: Why Technique Matters

Location: 436

Speaker: – University College London

10:15 AM - 12:15 PM PDT

S31.2- Virtually There: Reinventing Care Beyond Hospital Walls

Location: 436

Speaker: – Newcastle Hospitals NHS Trust

10:15 AM - 12:15 PM PDT

S31.3- Real Life Experience of Digital Health Platforms in Adults with CF

Location: 436

Speaker: – Royal Papworth Hospital NHS Foundation Trust and Cambridge University

10:15 AM - 12:15 PM PDT

S31.4- Navigating Wellness: Online Pulmonary Therapy for CF Patients

Location: 436

Speaker: – Inova Fairfax Hospital

10:15 AM - 12:15 PM PDT

S32.1- SORT lipids

Location: 427-429

Speaker:

10:15 AM - 12:15 PM PDT

S32.2- Peptide Targeted LNPs

Location: 427-429

Speaker: – college of pharmacy- Oregon state university

10:15 AM - 12:15 PM PDT

S32.3- Title TBD

Location: 427-429

Speaker: – University of Michigan

10:15 AM - 12:15 PM PDT

S32.4- Peptide Decorated LNPs for Targeted Airway Epithelial Delivery

Location: 427-429

Speaker: – Department of Genetics and Genomic Medicine, UCL Great Ormond Street Institute of Child Health,London, UK

10:15 AM - 12:15 PM PDT

S32--Gene Delivery: Targeted Nonviral Delivery to Airway Epithelial Cells

Location: 427-429

Chair: – University of Michigan

Chair: – Department of Genetics and Genomic Medicine, UCL Great Ormond Street Institute of Child Health,London, UK

PTAC/CFTR

10:15 AM - 12:15 PM PDT

W32--Lung Health in CF

Location: 433-434

Chair: – University of Alabama at Birmingham

Chair: – University of Michigan

CLIN

10:15 AM - 12:15 PM PDT

W32.1- Long term clinical effectiveness of elexacaftor/tezacaftor/ivacaftor (ETI) through 4.5 years of ETI therapy: PROMISE Cohort

Location: 433-434

Speaker: – University of Alabama at Birmingham

10:15 AM - 12:15 PM PDT

W32.2- Registry-based RCT to assess change in respiratory function for people with cystic fibrosis established on elexacaftor/tezacaftor/ivacaftor after withdrawal of nebulised mucoactive therapies: CF STORM

Location: 433-434

Speaker: – UCL Great Ormond Street Institute of Child Health

10:15 AM - 12:15 PM PDT

W32.3- Impact of gaps in ETI treatment in adults with CF

Location: 433-434

Speaker: – University of Washington

10:15 AM - 12:15 PM PDT

W32.4- A Cystic Fibrosis Foundation Patient Registry analysis of pulmonary exacerbations and lung function in pregnant versus non-pregnant females with cystic fibrosis

Location: 433-434

Speaker: – University of Texas Southwestern Medical Center

10:15 AM - 12:15 PM PDT

W32.5- Lung microbiome and clinical outcomes during antibiotic treatment of cystic fibrosis pulmonary exacerbations: Insights from the STOP2 trial

Location: 433-434

Speaker: – University of Michigan Medical School

10:15 AM - 12:15 PM PDT

W33--Non-Modulator Eligible/Advanced Lung Disease

Location: 435

Chair: – University of California Los Angeles (UCLA)

Chair: – University of Alabama at Birmingham

PT&RT

10:15 AM - 12:15 PM PDT

W33.1- title pending

Location: 435

Speaker:

10:15 AM - 12:15 PM PDT

W33.2 -Advanced Lung Disease documentation for Port CF

Location: 435

Speaker: – University Of Rochester Medical Center

10:15 AM - 12:15 PM PDT

W33.3- The lived experience & unmet needs of people with CF with genotypes not responsive to CFTR modulators: A mixed-methods study

Location: 435

Speaker: – Johns Hopkins University

10:15 AM - 12:15 PM PDT

W33.4- Engagement, Communication & Research Perspectives Among People with Cystic Fibrosis Not Benefiting from CFTR Modulators: Insights from a Two-Phase Qualitative Study

Location: 435

Speaker: – Cystic Fibrosis Foundation

10:15 AM - 12:15 PM PDT

W33.5- An updated look at a single adult CF center initiative to improve patient understanding of lung transplantation processes in collaboration with the transplant center.

Location: 435

Speaker: – The University of Michigan Transplant Center

10:15 AM - 12:15 PM PDT

W34--Restoring Airway Surface Physiology in CF

Location: Flex A

Chair: – Harvard Medical School

Chair: – University of Iowa

APPTT

10:15 AM - 12:15 PM PDT

W34.1- Physiologic Regeneration: Airway Hillocks Restore Appropriate Mucociliary Transport After Injury

Location: Flex A

Speaker: – Harvard Medical School

10:15 AM - 12:15 PM PDT

W34.2- Sputum viscoelastic properties and airway inflammation in cystic fibrosis on elexacaftor/tezacaftor/ivacaftor therapy are comparable to primary ciliary dyskinesia

Location: Flex A

Speaker: – Charité-Universitätsmedizin Berlin

10:15 AM - 12:15 PM PDT

W34.3- Pulmonary ionocytes regulate airway surface liquid pH, viscosity, and mucociliary clearance in the large airway in swine

Location: Flex A

Speaker: – University of Saskatchewan

10:15 AM - 12:15 PM PDT

W34.4- A 3D bioengineered human submucosal gland ductal model for studying mucociliary clearance in cystic fibrosis

Location: Flex A

Speaker: – Cedars-Sinai Medical Center

10:15 AM - 12:15 PM PDT

W34.5- MUC5AC plays an important role in maintaining airway mucociliary transport

Location: Flex A

Speaker: – The University of Iowa

10:15 AM - 12:15 PM PDT

W35--Navigating GI & Hepatic Challenges in CF: Current Insights & Future Directions

Location: Signature Room

Chair: – Levine Children's Hospital

Chair: – UT Southwestern

CLIN

10:15 AM - 12:15 PM PDT

W35.1- Hepatobiliary abnormalities and change in serum and imaging biomarkers in young children with CF before and after 12 months of elexacaftor/tezacaftor/ivacaftor: Interim Results from the BEGIN Study

Location: Signature Room

Speaker: – Baylor College of Medicine

10:15 AM - 12:15 PM PDT

W35.2- Pivotal Potential: Predictors of pancreatic function restoration in children with cystic fibrosis on CFTR modulators

Location: Signature Room

Speaker: – Division of Pediatric Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, Riley Hospital for Children, and Indiana University School of Medicine

10:15 AM - 12:15 PM PDT

W35.3- Hi, ETI; G tube goodbye: A retrospective review of removal of gastrostomy tubes after initiation of highly effective modulatory therapy in pediatric patients with cystic fibrosis

Location: Signature Room

Speaker: – Pediatrics, University of Texas Southwestern/Children's Medical Center of Dallas, Dallas, TX, USA

10:15 AM - 12:15 PM PDT

W35.4- Trends in pediatric ED visits and hospitalizations for gastrointestinal complications in pediatric patients with cystic fibrosis pre and post modulator therapy – A multicenter cohort analysis.

Location: Signature Room

Speaker: – Children's Hospital of Wisconsin

10:15 AM - 12:15 PM PDT

W35.5- Quantitative magnetic resonance imaging as an objective measure of hepatobiliary disease in cystic fibrosis: a pilot study

Location: Signature Room

Speaker: – Pediatrics, University of Texas Southwestern/Children's Medical Center of Dallas, Dallas, TX, USA

10:15 AM - 12:15 PM PDT

W36--Risky Behaviors in Adolescents & Young Adults with CF

Location: 420-422

Chair: – Nationwide Children's Hospital

Chair: – Cleveland Clinic Children's

NRS

10:15 AM - 12:15 PM PDT

W36.1- Beyond the mirror: Body image post CFTR modulator therapy

Location: 420-422

Speaker: – USC Keck Medical Center

10:15 AM - 12:15 PM PDT

W36.2- Exploring Body Image and Mental Health in Adults with Cystic Fibrosis in the Era of Highly Effective Modulator Therapies

Location: 420-422

Speaker: – Mayo Clinic Florida

10:15 AM - 12:15 PM PDT

W36.3- Improving Access to Rescue Medications for Adult CF Patients with High-Risk Medication Use

Location: 420-422

Speaker: – UofL Health Pulmonary Specialty Clinic

10:15 AM - 12:15 PM PDT

W36.4- Adapting the “Tobacco, Alcohol, Prescription medication, and other Substance use” (TAPS) Tool for use in a large adult cystic fibrosis center

Location: 420-422

Speaker: – Boston Children's Hospital

10:15 AM - 12:15 PM PDT

W36.5- Implementing the CRAFFT 2.1 screening tool into a pediatric Cystic Fibrosis clinic

Location: 420-422

Speaker: – Nemours Children's Health

10:15 AM - 12:15 PM PDT

W37--Managing CF, One Transition at A Time

Location: Ballroom 1

Chair: – Michigan Medicine

Chair: – University of Colorado SOM/Children's Hospital Colorado

SW/PSYCH

10:15 AM - 12:15 PM PDT

W37.1- Centering the patient voice in healthcare transition: Lessons learned from young adults with cystic fibrosis

Location: Ballroom 1

Speaker: – Boston Children's Hospital/Brigham and Women's Hospital

10:15 AM - 12:15 PM PDT

W37.2- Advance Care Planning in Cystic Fibrosis: Implementation of the Serious Illness Conversation Guide

Location: Ballroom 1

Speaker: – Stanford Health Care

10:15 AM - 12:15 PM PDT

W37.3- Bright Beginnings: Integrating Caregiver Emotional Support into Cystic Fibrosis Care

Location: Ballroom 1

Speaker: – Happy Heart Families

10:15 AM - 12:15 PM PDT

W37.4- Impact of parenthood on the pulmonary health of people with cystic fibrosis: findings from the HOPeCF retrospective cohort study

Location: Ballroom 1

Speaker: – University of Pittsburgh

10:15 AM - 12:15 PM PDT

W37.5- Aging concerns in the cystic fibrosis community

Location: Ballroom 1

Speaker: – Cystic Fibrosis Foundation

12:00 PM - 1:00 PM PDT

Poster Removal

12:30 PM - 2:00 PM PDT

LL07--Advocacy 101- How to Speak Up for Your Patients

Location: 333-334

Chair: – University of Kansas Health System

Chair: – Cystic Fibrosis Foundation

Speaker: – Cystic Fibrosis Foundation

HEACSW/PSYCH

12:30 PM - 2:00 PM PDT

LL08--Let's Get Physical: HIIT It Up

Location: 345-346

Chair: – University Hospitals Cleveland Medical Center

Chair: – Precision Performance Institute

Speaker: – JW Ruby Memorial Hospital, WVU Medicine

Speaker: – University Hospitals Cleveland Medical Center

Speaker:

PT&RT

12:30 PM - 2:00 PM PDT

LL09--Different Plans Toward the Same Destination: Tailoring Treatment to Patient Preferences

Location: 343-344

Chair: – UNC

Chair: – University of Colorado School of Medicine/Children's Hospital Colorado

Speaker: – Nemours Children's Health - Orlando

Speaker: – Medical College of Georgia/Augusta University

Speaker: – University of Kentucky

SW/PSYCH

12:30 PM - 2:00 PM PDT

LL10--Career Development: How to Review a Manuscript & Respond to a Manuscript Review

Location: 323-325

Chair: – Case Western Reserve University School of Medicine

Chair: – University of Calgary

Speaker: – Case Western Reserve University School of Medicine

Speaker: – University of Calgary

APPTT

12:30 PM - 2:00 PM PDT

LL11--Systemic Challenges to Care & Workarounds

Location: 340-342

Chair: – Cook Children's Pedi and Adult CF Center

Chair: – Boston Children's Hospital

Speaker: – Driscoll Children's Hospital

Speaker: – Boston Children's Hospital

Speaker: – Brigham and Women’s Hospital, Division of Global Health Equity

Speaker: – MedStar Washington Hospital Center

Speaker: – Children's National Hospital, 111 Michigan Avenue, NW Washington, DC 20010

SW/PSYCHHEAC

12:30 PM - 2:00 PM PDT

LL12--Antibiotics Strategies in the Post-modulator Era, A Pro/Con Discussion

Location: 335-336

Chair: – National Jewish Health

Chair: – Children’s National Hospital

Speaker: – University of Washington

Speaker: – University of Colorado

Speaker: – University of Leeds

IMI

12:30 PM - 2:00 PM PDT

Roundtables: Group 1

Location: 345 - 346

12:30 PM - 2:00 PM PDT

RT1.1- Navigating GI Cancers in CF: Screening, Diagnosis, & Management

Location: 345 - 346

Facilitator: – University Hospitals Cleveland Medical Center/Case Western Reserve University

CLIN

12:30 PM - 2:00 PM PDT

RT1.2- Disordered Eating/Eating Disorders

Location: 345 - 346

Facilitator: – Boston Children's Hospital, Harvard Medical School

CLIN

12:30 PM - 2:00 PM PDT

RT1.3- Methods for Engagement of Minoritized Communities in Clinical Research

Location: 345 - 346

Facilitator: – University of Washington

CLIN

12:30 PM - 2:00 PM PDT

RT1.4- Leveraging Your Network

Location: 345 - 346

Facilitator: – Cystic Fibrosis Foundation

CLIN

12:30 PM - 2:00 PM PDT

RT1.5- Thinking Outside the Box

Location: 345 - 346

Facilitator: – Stanford University

CLIN

12:30 PM - 2:00 PM PDT

RT1.6- EPIC & Oncore

Location: 345 - 346

Facilitator:

CLIN

12:30 PM - 2:00 PM PDT

RT1.7- Mental Health for RCs

Location: 345 - 346

Facilitator: – National Jewish Health

CLIN

12:30 PM - 2:00 PM PDT

RT1.8- Bloat is Goat: Understanding Symptoms & Management in CF

Location: 345 - 346

Facilitator: – The Children's Hospital of Philadelphia

CLIN

12:30 PM - 2:00 PM PDT

RT1.9- Feeding Challenges in CF: Navigating the Spectrum from Infancy to Adulthood

Location: 345 - 346

Facilitator: – Doernbecher Children's/Oregon Health & Science University

CLIN

12:30 PM - 2:00 PM PDT

RT1.10- Balancing Act: Managing PERT Therapy in the Era of HEMT

Location: 345 - 346

Facilitator: – University of Minnesota

CLIN

12:30 PM - 2:00 PM PDT

RT1.11- Tough Cases in CF Bone Disease

Location: 345 - 346

Facilitator: – Johns Hopkins University School of Medicine

CLIN

12:30 PM - 2:00 PM PDT

RT1.12- Understanding the Presence of DGBIs Amidst GI Manifestations of CF

Location: 345 - 346

Facilitator: – Emory/Children's Healthcare of Atlanta

CLIN

12:30 PM - 2:00 PM PDT

RT1.13- Liver Disease Blueprint: Turning Guidelines into Action

Location: 345 - 346

Facilitator: – UT Southwestern

CLIN

12:30 PM - 2:00 PM PDT

RT1.14- Hypoglycemia in CFRD

Location: 345 - 346

Facilitator: – University of Utah

CLIN

12:30 PM - 2:00 PM PDT

RT1.15- Practical CGM: Downloading & Interpreting Data

Location: 345 - 346

Facilitator:

CLIN

12:30 PM - 2:00 PM PDT

RT1.16- Insulin Pump Use in CFRD

Location: 345 - 346

Facilitator: – University of Michigan

CLIN

12:30 PM - 2:00 PM PDT

RT1.17- Pulmonary Function Testing: Tips & Tricks for Obtaining Quality Results

Location: 345 - 346

Facilitator: – Banner University Medicine - Tucson

CLIN

12:30 PM - 2:00 PM PDT

Roundtables: Group 2

Location: Elliott Bay

12:30 PM - 2:00 PM PDT

RT2.1- Neurodivergence & Impact on Nutrition

Location: Elliott Bay

Facilitator: – Emory Healthcare Cystic Fibrosis Center

NTR

12:30 PM - 2:00 PM PDT

RT2.2- Pediatric Nutrition 101

Location: Elliott Bay

Facilitator: – Children's Hospital Colorado

NTR

12:30 PM - 2:00 PM PDT

RT2.3- Screening for Diabetes, Including Hgb A1c Cutoffs

Location: Elliott Bay

Facilitator: – Joe Dimaggio Children's Hospital

NTR

12:30 PM - 2:00 PM PDT

RT2.4- Caring for the CF Caregiver

Location: Elliott Bay

Community Facilitator: – Realistic Expectations PLLC

SW/PSYCH

12:30 PM - 2:00 PM PDT

RT2.5- Alyftrek in Adults

Location: Elliott Bay

Facilitator: – Gunnar Esiason Adult Cystic Fibrosis and Lung Program at Columbia University Medical Center

SW/PSYCH

12:30 PM - 2:00 PM PDT

RT2.6- Addressing ASD in Clinic

Location: Elliott Bay

Facilitator: – Tulane Medical/ Manning Family Children's

SW/PSYCH

12:30 PM - 2:00 PM PDT

RT2.7- Alyftrek in Peds

Location: Elliott Bay

Facilitator:

SW/PSYCH

12:30 PM - 2:00 PM PDT

RT2.8- Disordered Eating

Location: Elliott Bay

Facilitator: – Adult CF Clinic Center, Geisinger Healthcare System

SW/PSYCH

12:30 PM - 2:00 PM PDT

RT2.9- Cell & Animal Models for Gene Therapy Applications

Location: Elliott Bay

Facilitator: – Emory University

PTAC/CFTR

12:30 PM - 2:00 PM PDT

Roundtables: Group 3

Location: 447 - 448

12:30 PM - 2:00 PM PDT

RT3.1- Murky Waters: Sifting Through Potential Risks & Benefits of CFTR Modulators in Transplant

Location: 447 - 448

Facilitator:

PHARM

12:30 PM - 2:00 PM PDT

RT3.2- Teaming Up to Tackle the Contraceptive Conundrum

Location: 447 - 448

Facilitator: – Northwell Health

PHARM

12:30 PM - 2:00 PM PDT

RT3.3- D'Oh No More Donuts! Changes to Medicare

Location: 447 - 448

Facilitator: – Keck Medicine of USC

PHARM

12:30 PM - 2:00 PM PDT

RT3.4- Oh Baby! CFTR Modulators in Pregnancy

Location: 447 - 448

Facilitator:

PHARM

12:30 PM - 2:00 PM PDT

RT3.5- CF Pharmacy Technician (Dos & Don'ts)

Location: 447 - 448

Facilitator: – Valley Children's Hospital

PHARM

12:30 PM - 2:00 PM PDT

RT3.6- How to Run a Successful Family Education Day

Location: 447 - 448

Facilitator: – Stanford University

NRS

12:30 PM - 2:00 PM PDT

RT3.7- QI Project on Improving PCP Access for CF Patients

Location: 447 - 448

Facilitator: – UC San Diego Health

NRS

12:30 PM - 2:00 PM PDT

RT3.8- Tips & Trick for Modified Modulator Dosing

Location: 447 - 448

Facilitator: – Phoenix Children's

NRS

12:30 PM - 2:00 PM PDT

RT3.9- Efficient Response & Process for Managing Patient Sick Calls

Location: 447 - 448

Facilitator: – CHOC

NRS

12:30 PM - 2:00 PM PDT

RT3.10- I Didn't Learn This in RT School

Location: 447 - 448

Facilitator: – University of Missouri

PT&RT

12:30 PM - 2:00 PM PDT

RT3.11- Inpatient Education Post HEMT

Location: 447 - 448

Facilitator: – Children's Nebraska

PT&RT

12:30 PM - 2:00 PM PDT

RT3.12- LCI Measurements

Location: 447 - 448

Facilitator: – Mountain State Cystic Fibrosis Center

PT&RT

12:30 PM - 2:00 PM PDT

RT3.13- Sputum Induction

Location: 447 - 448

Facilitator: – Adult CF Center of Central Texas

PT&RT

12:30 PM - 2:00 PM PDT

RT3.14- Collaboration Between Physical Therapy & Dietitians

Location: 447 - 448

Facilitator: – UH Rainbow Babies & Children's Hospital

PT&RT

1:00 PM - 2:00 PM PDT

Special Session-- CFF Research Funding Strategy & Priorities

Location: Ballroom 3

Speaker: – Cystic Fibrosis Foundation

Speaker:

2:30 PM - 3:45 PM PDT

PL3--Title: Until It’s Done for Everyone: Addressing Health Disparities & Transforming the International Landscape of Cystic Fibrosis Care

Location: Flex C

Speaker: – Jennifer L. Taylor-Cousar, MD, MSCS, ATSF

Speaker: – University of Alabama at Birmingham

7:00 PM - 10:00 PM PDT

Closing Event

5:00 AM - 6:00 AM PDT

PPC-- Advisors (Not a Session)

Program Committee: – Realistic Expectations PLLC

Program Committee: – CFF

Program Committee: – N/A

Program Committee: – Cystic Fibrosis Reproductive and Sexual Health Collaborative

5:00 AM - 6:00 AM PDT

PPC-- APPTT (Not a Session)

Program Committee: – Indiana University School of Medicine

Program Committee: – Washington University in St. Louis

Program Committee: – Department of Pediatrics, Emory University

Program Committee: – Case Western Reserve University School of Medicine

Program Committee: – University of Saskatchewan

Program Committee: – University of Cincinnati

Program Committee: – Marsico Lung Institute, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina

5:00 AM - 6:00 AM PDT

PPC-- CLIN (Not a Session)

Program Committee: – St. Michael's Hospital, Unity Health Toronto

Program Committee: – University of Washington

Program Committee: – UH Cleveland Medical Center / Rainbow Babies and Children's

Program Committee:

Program Committee: – Helen DeVos Children's Hospital @ Corewell Health

Program Committee: – UPMC Children's Hospital of Pittsburgh

Program Committee: – National Jewish Health

Program Committee: – Johns Hopkins University

Program Committee: – University of Texas Southwestern Medical Center

Program Committee: – Seattle Children's Hospital/UW

Program Committee: – University of British Columbia and St. Paul’s Hospital

Program Committee: – University of Alabama at Birmingham

Program Committee: – University of Alabama at Birmingham/Children's of Alabama

Program Committee: – Case Western Reserve University

Program Committee: – Pediatric Gastroenterology and Nutrition, University of Texas Southwestern/Children's Medical Center of Dallas, Dallas, TX, US

5:00 AM - 6:00 AM PDT

PPC-- EPP (Not a Session)

Program Committee:

Program Committee: – Case Western Reserve University

Program Committee: – Division of Pulmonary, Allergy & Immunology, Cystic Fibrosis, and Sleep Department of Pediatrics Emory University School of Medicine

Program Committee: – Saint Louis University

5:00 AM - 6:00 AM PDT

PPC-- IMI (Not a Session)

Program Committee: – The Hospital for Sick Children

Program Committee: – National Jewish Health

Program Committee: – Emory University/Childrens Atlanta

Program Committee: – University of Michigan Medical School

Program Committee: – University of Münster

Program Committee: – University at Buffalo

5:00 AM - 6:00 AM PDT

PPC-- NRS (Not a Session)

Program Committee: – Phoenix Children's Hospital

Program Committee: – Stanford University

Program Committee: – Rush University Medical Center

Program Committee: – University of Minnesota - Pediatric CF Center

Program Committee: – Medical University of SC

Program Committee: – Cohen Children's Medical Center

5:00 AM - 6:00 AM PDT

PPC-- PTAC/CFTR (Not a Session)

Program Committee:

Program Committee: – University of North Carolina at Chapel Hill

Program Committee: – Faculty of Sciences, University of Lisboa

Program Committee: – School of Physiology, Pharmacology and Neuroscience, University of Bristol

Program Committee: – University of North Carolina at Chapel Hill

Program Committee: – Johns Hopkins University

Program Committee: – University of Rochester School of Medicine and Dentistry

Program Committee: – CWRU

Program Committee: – Department of Genetic Medicine, Johns Hopkins University School of Medicine

5:00 AM - 6:00 AM PDT

PPC-- SW/PSYCH (Not a Session)

Program Committee: – Jacobs School of Medicine and Biomedical Sciences, University at Buffalo

Program Committee: – Oklahoma State University

Program Committee: – National Jewish Health

Program Committee: – The University of Michigan

5:00 AM - 6:00 AM PDT

PPC--HEAC (Not a Session)

Program Committee: – Seattle Children's Hospital

Program Committee: – University of Kansas Health System

Program Committee: – University of Virginia

Program Committee: – University of Rochester Medical Center

5:00 AM - 6:00 AM PDT

PPC--NTR (Not a Session)

Program Committee: – Alfred Health

Program Committee: – University Hospitals

Program Committee: – New York Presbyterian/Columbia University Irving Medical Center

Program Committee: – Massachusetts General Hospital

Program Committee: – University Health

5:00 AM - 6:00 AM PDT

PPC--PHARM (Not a Session)

Program Committee: – Riley Hospital for Children at Indiana Unversity Health

Program Committee: – Johns Hopkins

Program Committee: – University of Southern California

5:00 AM - 6:00 AM PDT

PPC--PT&RT (Not a Session)

Program Committee: – UAB/Children's of Alabama

Program Committee: – Johns Hopkins Hospital

Program Committee: – Binghamton University

Program Committee: – University Of Rochester Medical Center