W01--Pathogenesis of CF Airway Infection

Chair(s)

• 

  Jodi Corley, PhD, MS

  National Jewish Health
• 

  Sophie Darch

  University of South Florida

This session will showcase current advances in the understanding of the complex microbial and host dynamics that drive airway disease in CF. Featured presentations will explore how bacterial evolutionary processes, interspecies signaling, and host-microbiome interactions influence infection persistence and immune regulation in the CF airways.

Presentations:

• 7:45 AM - 9:45 AM PDT

  W01.1- C-di-GMP-dependent and -independent envelope stress response systems converge in Pseudomonas aeruginosa surface sensing
  

  Speaker: Megan O'Malley, PhD – University of Washington
• 7:45 AM - 9:45 AM PDT

  W01.2- CFTR mutation abrogates Prevotella mediated regulation of epithelial cell defense against Staphylococcus aureus
  

  Speaker: Sarah E. Clark, PhD – University of Colorado School of Medicine
• 7:45 AM - 9:45 AM PDT

  W01.3- Evolutionary diversification of Pseudomonas aeruginosa pre-infection impacts downstream host-pathogen interactions in a model of cystic fibrosis airway infection
  

  Speaker: Catherine R. Armbruster, PhD MPH – Carnegie Mellon University
• 7:45 AM - 9:45 AM PDT

  W01.4- Investigating the effects of the cystic fibrosis infant gut microbiota on immune regulation
  

  Speaker: Caitlin E. Murphy – Geisel School of Medicine at Dartmouth
• 7:45 AM - 9:45 AM PDT

  W01.5- Stenotrophomonas maltophilia exhibits defensive multicellularity in response to a Pseudomonas aeruginosa quorum sensing molecule
  

  Speaker: Stefan Katharios-Lanwermeyer, PhD, MPH – National Institutes of Health (NIH)