S12--PRenatal MOdulator Treatment to PrEvent CF ComplicaTions (PROTECT)

Chair(s)

• 

  Sylvia Szentpetery, MD, MPH

  Pediatric Pulmonary
  Medical University of South Carolina
• AR

  Andrea Roe, MD, MPH

  Obstetrics and Gynecology
  University of Pennsylvania Perelman School of Medicine

CFTR modulator use among pregnant women is increasing, including among individuals with CF, as well as those without CF but whose pregnancies have been diagnosed with CF . This session will highlight updates on information shared at the Cystic Fibrosis Foundation’s PROTECT workshop, including data from CF animal models treated with CFTR modulators, updates on CFTR modulator safety in both pregnant people with and without CF, as well as review of current U.S. and European case data. Members of the CF community will also share their related experiences.

Presentations:

• 2:30 PM - 4:30 PM PDT

  S12.1- “I Don’t Have CF but My Baby Does”: Experiences of Parents without CF Who Used CFTR Modulators During Pregnancy or Breastfeeding
  

  Speaker: Stephanie Marquart, MA – Living Roots Counseling

  Speaker: Lacey Norton – N/A
• 2:30 PM - 4:30 PM PDT

  S12.3- Effects of Highly Effective Modulator Therapy on CF Ferret Fertility and Pregnancy
  

  Speaker: John F. Engelhardt, PhD – University of Alabama at Birmingham
• 2:30 PM - 4:30 PM PDT

  S12.3- Safety of CFTR modulators in healthy controls and pregnant people with CF
  

  Speaker: Jennifer L. Taylor-Cousar, MD – Jennifer L. Taylor-Cousar, MD, MSCS, ATSF
• 2:30 PM - 4:30 PM PDT

  S12.4- Summary of US & European Case Studies: Fetal Treatment via CF Carrier Mothers
  

  Speaker: Sylvia E. Szentpetery, MD, MPH – Medical University of South Carolina