S27--Phage is the Rage: Demystifying Phage Therapy

Saturday, October 25, 2025

10:15 AM - 12:15 PM PDT

Location:Ballroom 3

Chair(s)

Isaac Martin, MBBS, MRCPCH, MD(Res)

The Hospital for Sick Children
Jonathan Koff

Department of Medicine
Yale University

This symposium explores cutting-edge advances in phage therapy for CF, highlighting genomic insights into bacterial resistance mechanisms, clinical-trial pipelines, pediatric-specific applications, NTM-targeted phages, and single‑sequential phage strategies. Attendees will gain a comprehensive understanding of translational efforts bridging genomic surveillance, compassionate use, and trial design to overcome antimicrobial resistance in CF.

Learning Objectives:

Evaluate current clinical trial and compassionate-use phage therapy strategies in CF.
Analyze genomic pathways of phage resistance in chronic CF pathogens.
Develop targeted phage approaches across CF populations and pathogens.

Presentations:

10:15 AM - 12:15 PM PDT

S27.1- Current status of phage therapy clinical trials
Speaker: Jerry A. Nick, Denver, CO, USA – National Jewish Health
10:15 AM - 12:15 PM PDT

S27.2- Phage therapy in pediatric pwCF
Speaker: Andrea Hahn, MD, MS – Children’s National Hospital
10:15 AM - 12:15 PM PDT

S27.3- NTM phages
Speaker: Katherine Wetzel, PhD – Georgia State University
10:15 AM - 12:15 PM PDT

S27.4- Single-sequential phage therapy for Pseudomonas in pwCF
Speaker: Katie Kortright, PhD – Yale University