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PT&RT
Session Type: Symposium

S21--For Your Consideration: A Debate on De-escalating Therapies? | Room: 427-429

Friday, October 24, 2025
2:30 PM - 4:30 PM PDT
Location:427-429

Recorded Session

This session will examine three foundational pillars of CF therapies: airway clearance, inhaled mucolytics and inhaled antibiotics for chronic pseudomonas. In the style of a pro/con debate, a panel of experts will debate the ‘pro’ and ‘con’ side of de-escalating these chronic therapies in the era of highly effective modulators.

Learning Objectives:

  • To examine the evidence for and against the de-escalation of inhaled mucolytic therapies.
  • To examine the evidence for and against the de-escalation of chronic pseudomonas treatment
  • To examine the evidence for and against the de-escalation of airway clearance

Presentations:

  • 2:30 PM - 4:30 PM PDT
    Pro Argument: De-Escalation of Airway Clearance

    Speaker: Mark Chilvers, MB ChB, MD MRCP, MRCPCH – BC Childrens Hospital

  • 2:30 PM - 4:30 PM PDT
    S21.2- Con Argument: De-Escalation of Airway Clearance

    Speaker: Gemma Stanford, PhD, B.Sc. Physiotherapy – Royal Brompton Hospital, Guys and St Thomas's NHS Foundation Trust and NHLI, Imperial College, London

  • 2:30 PM - 4:30 PM PDT
    S21.3- Pro Argument: De-Escalation of Mucolytics

    Speaker: Alex Gifford, MD – UH Cleveland Medical Center

  • 2:30 PM - 4:30 PM PDT
    S21.4- Con Argument: De-Escalation of Mucolytics

    Speaker: Scott H. Donaldson, MD – University of North Carolina at Chapel Hill

  • 2:30 PM - 4:30 PM PDT
    S21.5- Pro Argument: De-Escalation of Anti-Pseudomonals

    Speaker: Margaret Oates, Pharm.D, BCPPS – Wellstar MCG- Children's Hospital of Georgia

  • 2:30 PM - 4:30 PM PDT
    S21.6- Con Argument: De-Escalation of Anti-Pseudomonals

    Speaker: Hilary M. Vogt, PharmD, BCPPS – Riley Hospital for Children at Indiana University Health