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Special Session

Navigating the Past, Present, and Future of CFTR Dysfunction Through Sweat Chloride

Friday, October 24, 2025
12:30 PM - 1:30 PM PDT
Location: 343-344
Food Available for Session Attendees
Review the history and recent advances in understanding CFTR science
• Understand how sweat chloride drove and continues to drive the strategy of the Vertex CFTR modulator program
• Define the relationship between sweat chloride and clinical outcomes in natural history
Discuss the learnings from sweat chloride and CFTR Function in CFTR modulator clinical trials
• Review the mechanism of action of CFTR modulators
• Discuss the association between sweat chloride and clinical outcomes in CFTR modulator clinical trials

This session is not accredited for Continuing Education.

This session is supported by Vertex Pharmaceuticals, Inc. Exhibitors and supporters of NACFC include manufacturers of CF drugs, medical device companies, pharmacies, hospitals, and other related organizations. The Cystic Fibrosis Foundation does not support nor endorse the products or services of NACFC 2025 exhibitors and supporters.