Baylor College of Medicine
Dr. Daniel Leung is a Professor of Pediatrics with tenure within the Division of Gastroenterology, Hepatology, and Nutrition at Baylor College of Medicinewhere he serves as Director of Hepatology and Liver Transplant Medicine at Texas Children’s Hospital. He is a clinician-scientist with broad expertise in the field of pediatric hepatology who has devoted his career to the study and care of children with chronic fibroinflammatory, including cholestatic liver disorders and cystic fibrosis associated liver disease (CFLD). He has unique expertise in the validation of both serum and imaging biomarkers of CFLD and CFLD related clinical outcomes. Dr. Leung has served as co-lead PI of a CF Foundation/NIH-supported 5 year, multicenter, longitudinal, observational cohort study known as the Baby Observational and Nutritional Supplement Study (BONUS) that first identified a relative growth hormone deficiency as a potential missing link for the persistent height deficiencies in CF despite newborn screening and significantly higher caloric supplementation. He has also led an explant study which confirmed that over 90% of children with CF who received liver transplantation had non-cirrhotic obliterative portal venopathy, a finding which challenged the long-held theory that CFTR dysfunction within the biliary epithelium resulted in cirrhosis. He is currently a part of the BEGIN sub-investigator team, serving as liver substudy lead, exploring the impact of ETI on surrogates of liver health in young children.
S25.4- Liver Fibrosis Markers in CF
Friday, October 24, 2025
2:30 PM - 4:30 PM PDT