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Livestreamed Session
Livestreamed Session

NTR
Session Type: Symposium

S10--Pancreatic Puzzles & Nutrition Noodles: Untangling Modulator Nutrition Challenges

Thursday, October 23, 2025
2:30 PM - 4:30 PM PDT
Location:427-429

With the advent of highly effective CFTR modulators (HEMT), the nutritional landscape of cystic fibrosis (CF) is rapidly evolving. This session untangles the complex interplay between pancreatic function, the gut microbiome, liver health, and nutrition interventions in the era of HEMT. From refining how we assess exocrine pancreatic sufficiency to understanding shifts in the CF diet-gut-lung and gut-liver axes and adapting nutrition care plans accordingly, these presentations aim to equip clinicians and researchers with the latest evidence and tools to deliver precise, personalized care. Emphasis will be placed on practical strategies to simplify and streamline nutrition support as clinical profiles shift under modulator therapy.

Learning Objectives:

  • Evaluate current and emerging methods for assessing pancreatic function, including fecal elastase and other biomarkers.
  • Describe the current and emerging evidence on the gut microbiome and the evolving profile of metabolic dysfunction-associated liver disease (MAFLD) in CF.
  • Identify evidence-based strategies to simplify and individualize nutrition interventions in people with CF receiving HEMT, including de-escalation of monitoring and nutrition therapies

Presentations:

  • 2:30 PM - 4:30 PM PDT
    S10.1- Measurement of Pancreatic Status: Fecal Elastase and Beyond

    Speaker: Senthil SankaraRaman, MD – Cleveland Clinic Children's Hospital

  • 2:30 PM - 4:30 PM PDT
    S10.2- Update on CF Gut Microbiome

    Speaker: (Keith) Chee Y. Ooi, MBBS, PhD, FRACP, AGAF – University of New South Wales & Sydney Children's Hospital

  • 2:30 PM - 4:30 PM PDT
    S10.3- CF Liver Disease in the Setting of Modulators: Special Focus on Metabolic Dysfunction-associated Fatty Liver Disease (MAFLD)

    Speaker: Sara Hassan, MD – UTSW (University of Texas Southwestern)

  • 2:30 PM - 4:30 PM PDT
    S10.4- Simplifying Nutrition Interventions in the Setting of HEMT: When and How Do We Do This?

    Speaker: Tamarah Katz, MSc (Nutr and Diet) – School of Clinical Medicine, Discipline of Paediatrics & Child Health, UNSW Medicine & Health, University of New South Wales, Australia